PLP1 anticorps (C-Term)

N° du produit ABIN119026

Cet anticorps Souris Monoclonal détecte spécifiquement PLP1 dans WB, FACS, IF, IHC (p) et IHC (fro). Il présente une réactivité envers Humain, Boeuf (Vache) et Mammifères.

Aperçu rapide pour PLP1 anticorps (C-Term) (ABIN119026)

Antigène: PLP1 (Proteolipid Protein 1 (PLP1))

Reactivité: Humain, Boeuf (Vache), Mammifères

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PLP1 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: Plpc1

Détail du produit anti-PLP1 anticorps

Épitope: C-Term

Specificité: This antibody recognizes Myelin Proteolipid protein (PLP) in many Mammalian species. This antibody also recognizes DM20.

Réactivité croisée (Details): Species reactivity (tested):Bovine.

Purification: Affinity Chromatography on Protein A from Tissue Culture Supernatant

Immunogène: Synthetic peptide CGRGTKF corresponding to C-terminal region of Myelin Proteolipid Protein. Spleen cells from immunised BALB/c mice were fused with cells of the mouse SP2/0 myeloma cell line.

Isotype: IgG2a

Information d'application

Indications d'application: Western blot. Immunohistochemistry on Frozen Sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur PLP1

Antigène: PLP1 (Proteolipid Protein 1 (PLP1))

Autre désignation: PLP1

Sujet: Myelin proteins are associated with the central nervous system (CNS) and play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. The proteolipid protein (PLP) and its splice variant DM20 are the predominant myelin proteins in the CNS. PLP is also one of the most extensively studied myelin proteins because of the prevelance of PLP mutations amongst humans and animals. Such mutations can lead to abnormal myelin formation resulting in conditions such as X-linked Pelizaeus-Merzbacher disease and spastic paraplegia type 2. PLP encodes the major protein components of compact CNS myelin and mutations in the PLP gene can lead to severe dysmyelinating disease.Synonyms: Lipophilin, Myelin proteolipid protein, PLP

ID gène: 281410

NCBI Accession: NP_776574

UniProt: P04116