PLP1 anticorps (C-Term)

N° du produit ABIN119026

Détail du produit anti-PLP1 anticorps

Antigène: PLP1 (Proteolipid Protein 1 (PLP1))

Épitope: C-Term

Reactivité: Humain, Boeuf (Vache), Mammifères

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PLP1 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificité: This antibody recognizes Myelin Proteolipid protein (PLP) in many Mammalian species. This antibody also recognizes DM20.

Réactivité croisée (Details): Species reactivity (tested):Bovine.

Purification: Affinity Chromatography on Protein A from Tissue Culture Supernatant

Immunogène: Synthetic peptide CGRGTKF corresponding to C-terminal region of Myelin Proteolipid Protein. Spleen cells from immunised BALB/c mice were fused with cells of the mouse SP2/0 myeloma cell line.

Clone: Plpc1

Isotype: IgG2a

Information d'application

Indications d'application: Western blot. Immunohistochemistry on Frozen Sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur PLP1

Antigène: PLP1 (Proteolipid Protein 1 (PLP1))

Autre désignation: PLP1 (PLP1 Produits)

Synonymes: anticorps GPM6C, anticorps HLD1, anticorps MMPL, anticorps PLP, anticorps PLP/DM20, anticorps PMD, anticorps SPG2, anticorps Plp, anticorps PLP1, anticorps plp1, anticorps DKFZp459O081, anticorps DKFZp459O113, anticorps DM20, anticorps jimpy, anticorps jp, anticorps msd, anticorps rsh, anticorps plp, anticorps hld1, anticorps mmpl, anticorps plp1a, anticorps pmd, anticorps spg2, anticorps DMalpha2c, anticorps wu:fc27f01, anticorps wu:fj36d03, anticorps wu:fj42d08, anticorps zgc:110499, anticorps PLP-B, anticorps plp1-a, anticorps plp1-b, anticorps plp1b, anticorps proteolipid protein 1, anticorps proteolipid protein (myelin) 1, anticorps myelin proteolipid protein, anticorps proteolipid protein 1 L homeolog, anticorps proteolipid protein 1a, anticorps proteolipid protein 1 S homeolog, anticorps PLP1, anticorps Plp1, anticorps plp1, anticorps Tsp_11640, anticorps plp, anticorps plp1.L, anticorps plp1a, anticorps plp1.S

Sujet: Myelin proteins are associated with the central nervous system (CNS) and play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. The proteolipid protein (PLP) and its splice variant DM20 are the predominant myelin proteins in the CNS. PLP is also one of the most extensively studied myelin proteins because of the prevelance of PLP mutations amongst humans and animals. Such mutations can lead to abnormal myelin formation resulting in conditions such as X-linked Pelizaeus-Merzbacher disease and spastic paraplegia type 2. PLP encodes the major protein components of compact CNS myelin and mutations in the PLP gene can lead to severe dysmyelinating disease.Synonyms: Lipophilin, Myelin proteolipid protein, PLP

ID gène: 281410

NCBI Accession: NP_776574

UniProt: P04116