MADCAM1 anticorps

N° du produit ABIN119567

Détail du produit anti-MADCAM1 anticorps

Antigène: MADCAM1 (Mucosal Vascular Addressin Cell Adhesion Molecule 1 (MADCAM1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MADCAM1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA), Functional Studies (Func)

Specificité: This antibody recognises MAdCAM-1 (mucosal addressin cell adhesion molecule -1), a 40 kDa protein expressed by vascular endothelium. Clone CA102.2C1 has been reported to block the binding of human cells expressing alpha4 Beta7 to immobilized MAdCAM-1 in vitro.

Purification: Affinity chromatography on Protein A

Immunogène: Bacterially expressed human MAdCAM-1.

Clone: CA102-2C1

Isotype: IgG1

Information d'application

Indications d'application: ELISA. Western blotting. Functional assay.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS

Agent conservateur: Azide free

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody at -20 °C. Ship at 2 - 8 °C.

Détails sur MADCAM1

Antigène: MADCAM1 (Mucosal Vascular Addressin Cell Adhesion Molecule 1 (MADCAM1))

Autre désignation: MAdCAM1 (MADCAM1 Produits)

Synonymes: anticorps MACAM1, anticorps AV211525, anticorps mucosal vascular addressin cell adhesion molecule 1, anticorps MADCAM1, anticorps Madcam1

Sujet: MAdCAM1 is an endothelial cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM1 (alpha4 beta7), L selectin, and VLA4 (alpha4 beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues. It is a member of the immunoglobulin family and is similar to ICAM1 and VCAM1. At least seven alternatively spliced transcripts encoding different protein isoforms have been found for this gene, but the full length nature of some variants has not been determined.Synonyms: MAdCAM-1, Mucosal addressin cell adhesion molecule 1, hMAdCAM-1

ID gène: 8174

NCBI Accession: NP_570116

UniProt: Q13477