DAXX anticorps (C-Term)
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- Antigène Voir toutes DAXX Anticorps
- DAXX (Death-Domain Associated Protein (DAXX))
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Épitope
- AA 558-740, C-Term
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Reactivité
- Humain, Souris
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp DAXX est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF)
- Specificité
- The antibody reacts with Daxx, a death domain containing protein mainly expressed in fetal and adult tissue.
- Purification
- Affinity Chromatography on Protein-A.
- Immunogène
- Recombinant C-terminal part (aa 558-740) of Human Daxx
- Clone
- DAXX-01
- Isotype
- IgG1
- Top Product
- Discover our top product DAXX Anticorps primaire
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- Indications d'application
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Western Blot. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH ~7.4 with 15 mM Sodium Azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- DAXX (Death-Domain Associated Protein (DAXX))
- Autre désignation
- DAXX (DAXX Produits)
- Synonymes
- anticorps BING2, anticorps DAP6, anticorps EAP1, anticorps LOC100226911, anticorps daxx, anticorps si:dz179b20.7, anticorps wu:fd15c03, anticorps death domain associated protein, anticorps Fas death domain-associated protein, anticorps 28S ribosomal protein S29, mitochondrial, anticorps death-domain associated protein, anticorps death-associated protein 6 L homeolog, anticorps DAXX, anticorps Daxx, anticorps LOC100226911, anticorps daxx.L, anticorps daxx
- Sujet
- Daxx is an apoptosis-modulating death-domain associated protein with functions in transcriptional regulation. Daxx functions bot in cytoplasm, where it interacts with Fas, and in nucleus (residing in PML oncogenic domains), where it is involved in SUMO-dependent regulation of transcription and subnuclear compartmentalization. Daxx senzitizes the cells to apoptosis, but on the other hand, this protein may also serve in preventing apoptosis in the early embryo. Even regarding the transcription, Daxx can serve both as a corepressor and a coactivator. During ischemic stress, Daxx translocates from the nucleus to the cytoplasm, where in regulates sodium hydrogen exchanger isoform 1 (NHE1).Synonyms: BING2, DAP6, Death domain-associated protein 6, EAP1, ETS1-associated protein 1, Fas death domain-associated protein
- ID gène
- 1616
- NCBI Accession
- NP_001135441
- UniProt
- Q9UER7
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway
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