Calcitonin Receptor anticorps (Cytoplasmic Domain)

N° du produit ABIN119693

L’anticorps Souris Monoclonal anti-Calcitonin Receptor a été validé pour WB, IF, FACS, IHC (p), IHC (fro) et EIA. Il convient pour détecter Calcitonin Receptor dans des échantillons de Humain et Lapin.

Aperçu rapide pour Calcitonin Receptor anticorps (Cytoplasmic Domain) (ABIN119693)

Antigène: Calcitonin Receptor (CALCR)

Reactivité: Humain, Lapin

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Calcitonin Receptor est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Clone: 31-01-14

Détail du produit anti-Calcitonin Receptor anticorps

Épitope: Cytoplasmic Domain

Specificité: This antibody recognizes the Calcitonin Receptor. Clone 31/01 recognizes an epitope within the cytoplasmic domain that is common to both C1a and C1b Human isoforms.

Purification: Affinity Chromatography on Protein A.

Immunogène: Synthetic peptide derived from a sequence within the cytoplasmic domain of Human Calcitonin Receptor. Spleen cells from immunised mice were fused with cells of the mouse SP2/0 myeloma cell line.

Isotype: IgG2a

Information d'application

Indications d'application: ELISA: 1/1000 - 1/5000. Immunohistochemistry on paraffin sections: 1/50 - 1/500, we recommend the use of 4 % paraformaldehyde fixation, rather than formalin fixation, This product does not require protein digestion pre-treatment of paraffin embedded sections, This product does not require antigen retrieval using heat treatment prior to staining of paraffin embedded sections. Recommended Positive Control: Kidney.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Calcitonin Receptor

Antigène: Calcitonin Receptor (CALCR)

Autre désignation: Calcitonin Receptor

Sujet: Calcitonin receptor is a membrane protein with seven transmembrane domains that is coupled to G protein messenger systems. The calcitonin receptor is expressed in kidney, central and peripheral nervous systems and on osteoclasts. It is also expressed in a number of tissues during the development of the embryo and may be important in foetal morphogenesis.Synonyms: CALCR, CT-R, CTR

ID gène: 799

NCBI Accession: NP_001158209

UniProt: P30988

Pathways: cAMP Metabolic Process