Calcitonin Receptor anticorps (Cytoplasmic Domain)
Aperçu rapide pour Calcitonin Receptor anticorps (Cytoplasmic Domain) (ABIN119693)
Antigène
Voir toutes Calcitonin Receptor (CALCR) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- Cytoplasmic Domain
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Specificité
- This antibody recognizes the Calcitonin Receptor. Clone 31/01 recognizes an epitope within the cytoplasmic domain that is common to both C1a and C1b Human isoforms.
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Purification
- Affinity Chromatography on Protein A.
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Immunogène
- Synthetic peptide derived from a sequence within the cytoplasmic domain of Human Calcitonin Receptor. Spleen cells from immunised mice were fused with cells of the mouse SP2/0 myeloma cell line.
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Isotype
- IgG2a
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Indications d'application
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ELISA: 1/1000 - 1/5000. Immunohistochemistry on paraffin sections: 1/50 - 1/500, we recommend the use of 4 % paraformaldehyde fixation, rather than formalin fixation, This product does not require protein digestion pre-treatment of paraffin embedded sections, This product does not require antigen retrieval using heat treatment prior to staining of paraffin embedded sections. Recommended Positive Control: Kidney.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS containing 0.09 % Sodium Azide as preservative
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Calcitonin Receptor (CALCR)
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Autre désignation
- Calcitonin Receptor
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Sujet
- Calcitonin receptor is a membrane protein with seven transmembrane domains that is coupled to G protein messenger systems. The calcitonin receptor is expressed in kidney, central and peripheral nervous systems and on osteoclasts. It is also expressed in a number of tissues during the development of the embryo and may be important in foetal morphogenesis.Synonyms: CALCR, CT-R, CTR
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ID gène
- 799
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NCBI Accession
- NP_001158209
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UniProt
- P30988
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Pathways
- cAMP Metabolic Process
Antigène
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