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CD177 anticorps

L’anticorps Souris Monoclonal anti-CD177 a été validé pour WB, FACS et IP. Il convient pour détecter CD177 dans des échantillons de Humain et Primate.
N° du produit ABIN119768

Aperçu rapide pour CD177 anticorps (ABIN119768)

Antigène

Voir toutes CD177 Anticorps
CD177 (CD177 Molecule (CD177))

Reactivité

  • 50
  • 7
  • 5
  • 4
  • 3
  • 3
  • 3
Humain, Primate

Hôte

  • 31
  • 23
  • 1
Souris

Clonalité

  • 34
  • 21
Monoclonal

Conjugué

  • 26
  • 7
  • 6
  • 5
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp CD177 est non-conjugé

Application

  • 30
  • 22
  • 13
  • 13
  • 10
  • 5
  • 4
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP)

Clone

MEM-166
  • Specificité

    This antibody reacts with CD177 (Neutrophil specific antigen 1), a 60 kDa GPI-linked cell surface glycoprotein of uPAR family, expressed on granulocytes and in bone marrow early erythroblasts, megakaryocytes, promyelocytes and myelocytes.

    Réactivité croisée (Details)

    Species reactivity (tested):Human, Non-Human Primates.

    Purification

    Affinity Chromatography on Protein A

    Immunogène

    Human Granulocytes

    Isotype

    IgG1
  • Indications d'application

    Flow cytometry. Immunoprecipitation. Western Blot under non-reducing conditions.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Concentration

    1.0 mg/mL

    Buffer

    PBS, pH ~7.4, 15 mM Sodium Azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated thawing and freezing.

    Stock

    4 °C/-20 °C

    Stockage commentaire

    Store the original vial at 2-8 °C, stock solution or aliquots thereof at -20 °C.
  • Antigène

    CD177 (CD177 Molecule (CD177))

    Autre désignation

    CD177

    Sujet

    CD177 (NB1/HNA-2a and PRV-1 form) is a GPI-anchored glycoprotein present mainly on neutrophils. Its plasma membrane expression is increased during pregnancy and inflammation or after G-CSF application. Ligand of CD177 has been identified as CD31(PECAM-1). CD177 participates in neutrophil transmigration and seems to be also a pro-proliferative molecule. The antibodies against CD177 can be involved in neonatal alloimmune neutropenia (NAN).Synonyms: HNA-2a, HNA2a, Human neutrophil alloantigen 2a, NB1, NB1 glycoprotein, PRV1, Polycythemia rubra vera protein 1

    ID gène

    57126

    NCBI Accession

    NP_065139

    UniProt

    Q8N6Q3
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