CD177 anticorps

N° du produit ABIN119768

L’anticorps anti-CD177 Monoclonal Souris est utilisé pour la détection de CD177 dans des échantillons de Humain et Primate. Il a été validé pour WB, FACS et IP.

Aperçu rapide pour CD177 anticorps (ABIN119768)

Antigène: CD177 (CD177 Molecule (CD177))

Reactivité: Humain, Primate

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD177 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP)

Clone: MEM-166

Détail du produit anti-CD177 anticorps

Specificité: This antibody reacts with CD177 (Neutrophil specific antigen 1), a 60 kDa GPI-linked cell surface glycoprotein of uPAR family, expressed on granulocytes and in bone marrow early erythroblasts, megakaryocytes, promyelocytes and myelocytes.

Réactivité croisée (Details): Species reactivity (tested):Human, Non-Human Primates.

Purification: Affinity Chromatography on Protein A

Immunogène: Human Granulocytes

Isotype: IgG1

Information d'application

Indications d'application: Flow cytometry. Immunoprecipitation. Western Blot under non-reducing conditions.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, pH ~7.4, 15 mM Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated thawing and freezing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the original vial at 2-8 °C, stock solution or aliquots thereof at -20 °C.

Détails sur CD177

Antigène: CD177 (CD177 Molecule (CD177))

Autre désignation: CD177

Sujet: CD177 (NB1/HNA-2a and PRV-1 form) is a GPI-anchored glycoprotein present mainly on neutrophils. Its plasma membrane expression is increased during pregnancy and inflammation or after G-CSF application. Ligand of CD177 has been identified as CD31(PECAM-1). CD177 participates in neutrophil transmigration and seems to be also a pro-proliferative molecule. The antibodies against CD177 can be involved in neonatal alloimmune neutropenia (NAN).Synonyms: HNA-2a, HNA2a, Human neutrophil alloantigen 2a, NB1, NB1 glycoprotein, PRV1, Polycythemia rubra vera protein 1

ID gène: 57126

NCBI Accession: NP_065139

UniProt: Q8N6Q3