CD226 anticorps

N° du produit ABIN119798

L’anticorps Souris Monoclonal anti-CD226 a été validé pour FACS et IP. Il convient pour détecter CD226 dans des échantillons de Humain.

Aperçu rapide pour CD226 anticorps (ABIN119798)

Antigène: CD226

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD226 est non-conjugé

Application: Flow Cytometry (FACS), Immunoprecipitation (IP)

Clone: DX11

Détail du produit anti-CD226 anticorps

Specificité: This antibody recognises CD226. Clone DX11 is reported to inhibit T- and NK cell mediated cytotoxicity against tumour cell targets and to block TNF alpha and IFN gamma secretion by alloantigen-specific T-cells. We recommend the use of SM2023A for funtional studies.

Purification: Affinity chromatography on Protein G

Immunogène: Human cytotoxic T lymphocyte clone. Spleen cells from immunised BALB/c mouse were fused with cells of the Sp2/0 myeloma cell line.

Isotype: IgG1

Information d'application

Indications d'application: Flow Cytometry: 1/50 - 1/200, Use 10 μL of the suggested working dilution to label 1 x 10^6 cells in 100 μL. Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur CD226

Antigène: CD226

Autre désignation: CD226 / DNAM1

Sujet: CD226 is a 65kD glycoprotein, also known as DNAM1 (DNAX accessory molecule-1). CD226 is broadly expressed on T-cells, NK cells, platelets, monocytes and a subset of B cells. CD226 is also expressed by a subset of CD3 positive thymocytes.Synonyms: DNAM-1, DNAX accessory molecule 1

ID gène: 10666

NCBI Accession: NP_006557

UniProt: Q15762

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints