LAIR1 anticorps
Aperçu rapide pour LAIR1 anticorps (ABIN119871)
Antigène
Voir toutes LAIR1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- This antibody recognises leukocyte-associated Ig-like receptor-1 (LAIR-1). Clone NKTA255 is reported to inhibit NK cell triggering via CD16 Molecules (See Poggi, A. et al.for details). We recommend the use of Azide Free Antibody Cat.-No SM2048A for this purpose. see Poggi, A. et al. for details.
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Purification
- Affinity Chromatography on Protein G
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Immunogène
- NK cells lines B12.100 and AM.25. Spleen cells from immunised mice were fused with cells of the P3U1 myeloma cell line.
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Isotype
- IgG1
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Indications d'application
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Flow Cytometry: 1/50 - 1/100, Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Immunoprecipitation. Western Blot: this antibody detects a band of approximately 40 kDa.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS, pH 7.4, 0.09 % Sodium Azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- LAIR1 (Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1))
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Autre désignation
- CD305 / LAIR1
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Sujet
- LAIR-1 is a 40kD cell surface molecule that functions as an inhibitory receptor on natural killer cells, monocytes and T cells. LAIR-1, otherwise known as CD305, is also expressed by other haematopoeitic cells including B cells, but is not expressed by nonhaematopoietic, platelets or erythrocytes.Synonyms: LAIR-1, Leukocyte-associated immunoglobulin-like receptor 1, hLAIR1
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ID gène
- 3903
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NCBI Accession
- NP_002278
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UniProt
- Q6GTX8
Antigène
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