Fc epsilon RI/FCER1A anticorps

N° du produit ABIN120271

Cet anticorps Souris Monoclonal détecte spécifiquement Fc epsilon RI/FCER1A dans FACS, WB, IP, IF, IHC (p) et EIA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Fc epsilon RI/FCER1A anticorps (ABIN120271)

Antigène: Fc epsilon RI/FCER1A (FCER1A) (Fc Fragment of IgE Receptor Ia (FCER1A))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Fc epsilon RI/FCER1A est non-conjugé

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Clone: 9-00E-001

Détail du produit anti-Fc epsilon RI/FCER1A anticorps

Specificité: SM2251P recognises the high affinity Fc receptor for IgE (Fc epsilon R1), which plays a central role in the IgE-mediated allergic response. Clone 9E1 specifically recognises the extracellular D1 domain of the Fc epsilon R1 alpha chain.

Purification: Affinity Chromatography on Protein G

Immunogène: CCR7 Rat basophilic leukaemia (RBL)-2H3 transfectants. Spleen cells from immunised Balb/c mice were fused with cells of the Sp2/0-Ag14 myeloma cell line.

Isotype: IgG2b

Information d'application

Indications d'application: ELISA. Western Blot. Immunoprecipitation. Immunofluorescence. Flow Cytometry: 1/25 - 1/50, Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4, 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Fc epsilon RI/FCER1A

Antigène: Fc epsilon RI/FCER1A (FCER1A) (Fc Fragment of IgE Receptor Ia (FCER1A))

Autre désignation: FCER1A

Sujet: Fc epsilon R1 consists of four subunits, a high affinity IgE binding alpha subunit, a beta chain and two di-sulphide linked gamma subunits. Fc epsilon R1 is primarily expressed on mast cells and basophils but expression of Fc epsilon R1 has also been reported on monocytes, Langerhans cells and dendritic cells from patients with atopic diseases.Synonyms: FCE1A, Fc-epsilon RI-alpha, FcERI, High affinity immunoglobulin epsilon receptor subunit alpha, IgE Fc receptor subunit alpha

ID gène: 2205

NCBI Accession: NP_001992

UniProt: P12319

Pathways: Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process