2B4 anticorps
Aperçu rapide pour 2B4 anticorps (ABIN120312)
Antigène
Voir toutes 2B4 (CD244) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- This antibody is specific for the CD244 cell surface antigen, also known as natural killer receptor 2B4 (NKG2B4).
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Purification
- Affinity Chromatography on Protein G.
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Immunogène
- CD244 Fusion protein. Spleen cells from immunised Balb/c mice were fused with cells of the NS-1 myeloma cell line.
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Isotype
- IgG1
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Indications d'application
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Flow Cytometry: Use 10 μL of 1/50-1/200 diluted antibody to label 106 cells in 100 μL. Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))
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Autre désignation
- CD244
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Sujet
- The glycoprotein CD244 is a member of the SLAM family of receptors which is expressed on natural killer (NK) cells, gamma delta T cells, CD14+ monocytes, and a subset of CD8+ T cells. CD244 was originally identified as an activating receptor on NK cells, although recent studies suggest that the receptor may have a wide range of activities including NK cell activation, costimulation, or even inhibition, depending on the cell type and stage of differentiation. The ligand of 2B4 is CD48, a GPI-anchored membrane protein also belonging to the SLAM family.Synonyms: NAIL, NK cell activation-inducing ligand, NK cell type I receptor protein 2B4, NKR2B4, Natural killer cell receptor 2B4
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ID gène
- 51744
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NCBI Accession
- NP_001160135
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UniProt
- Q9BZW8
Antigène
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