2B4 anticorps (PE)
Aperçu rapide pour 2B4 anticorps (PE) (ABIN120314)
Antigène
Voir toutes 2B4 (CD244) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- This antibody is specific for the CD244 cell surface antigen, also known as natural killer receptor 2B4 (NKG2B4).
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Purification
- Affinity chromatography on Protein G
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Immunogène
- CD244 Fusion protein. Spleen cells from immunised Balb/c mice were fused with cells of the NS-1 myeloma cell line.
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Isotype
- IgG1
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Indications d'application
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Flow Cytometry: neat - 1/10, use 10 μL of the suggested working dilution to label 106 cells in 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Reconstitution
- Restore with 1.0 mL distilled water
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Concentration
- 0.1 mg/mL
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Buffer
- PBS, pH 7.4 containing 0.09 % Sodium Azide and 1 % Bovine Serum Albumin
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- -20 °C
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Stockage commentaire
- Can be shipped at 2-8 °C. Upon arrival store (in aliquots) at -20 °C.
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- 2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))
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Autre désignation
- CD244
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Sujet
- The glycoprotein CD244 is a member of the SLAM family of receptors which is expressed on natural killer (NK) cells, gamma delta T cells, CD14+ monocytes, and a subset of CD8+ T cells. CD244 was originally identified as an activating receptor on NK cells, although recent studies suggest that the receptor may have a wide range of activities including NK cell activation, costimulation, or even inhibition, depending on the cell type and stage of differentiation. The ligand of 2B4 is CD48, a GPI-anchored membrane protein also belonging to the SLAM family.Synonyms: NAIL, NK cell activation-inducing ligand, NK cell type I receptor protein 2B4, NKR2B4, Natural killer cell receptor 2B4
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ID gène
- 51744
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NCBI Accession
- NP_001160135
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UniProt
- Q9BZW8
Antigène
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