LAG3 anticorps
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- Antigène Voir toutes LAG3 Anticorps
- LAG3 (Lymphocyte-Activation Gene 3 (LAG3))
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Reactivité
- Souris
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Hôte
- Rat
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp LAG3 est non-conjugé
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Application
- Flow Cytometry (FACS), Functional Studies (Func)
- Specificité
- This antibody recognises lymphocyte activation gene-3 (LAG-3) that is also referred to as CD223. Clone C9B7W recognises an epitope within the D2 domain of CD223. The antibody is reported to block the in vitro function of murine LAG-3 but studies suggest that the antibody does not block binding of LAG-3 to MHC class II.
- Purification
- Affinity chromatography on Protein G
- niveau d'endotoxine
- Low Endotoxin
- Immunogène
- Murine CD223 Ig fusion protein. Cells from immunised Lewis rats were fused with cells of the Sp/20 myeloma cell line.
- Clone
- C9B7W
- Isotype
- IgG1
- Top Product
- Discover our top product LAG3 Anticorps primaire
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anti-Lymphocyte-Activation Gene 3 (LAG3) (AA 103-132) antibody
LAG3 Reactivité: Humain, Souris WB, FACS, IHC (p) Hôte: Lapin Polyclonal RB21775 unconjugated
anti-Lymphocyte-Activation Gene 3 (LAG3) antibodyLAG3 Reactivité: Humain WB, ELISA, IHC, FACS, ICC, Neut Hôte: Souris Monoclonal 3A4A10 unconjugated
anti-Lymphocyte-Activation Gene 3 (LAG3) (AA 103-132) antibodyLAG3 Reactivité: Humain WB, ELISA, IHC Hôte: Lapin Polyclonal unconjugated
anti-Lymphocyte-Activation Gene 3 (LAG3) (AA 29-450) antibodyLAG3 Reactivité: Humain WB, ELISA, IHC, FACS Hôte: Souris Monoclonal 8B12E10 unconjugated
anti-Lymphocyte-Activation Gene 3 (LAG3) (N-Term) antibodyLAG3 Reactivité: Humain WB, ELISA, IHC, IP, FACS, ICC Hôte: Souris Monoclonal L4-PL33 unconjugated
anti-Lymphocyte-Activation Gene 3 (LAG3) (AA 1-360) antibodyLAG3 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
anti-Lymphocyte-Activation Gene 3 (LAG3) (AA 244-487) antibodyLAG3 Reactivité: Humain WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-Lymphocyte-Activation Gene 3 (LAG3) (AA 209-451) antibodyLAG3 Reactivité: Rat WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-Lymphocyte-Activation Gene 3 (LAG3) (AA 29-450) antibodyLAG3 Reactivité: Humain WB, ELISA, IF Hôte: Lapin Polyclonal unconjugated
anti-Lymphocyte-Activation Gene 3 (LAG3) (AA 201-300) antibodyLAG3 Reactivité: Humain, Souris WB, ELISA, ICC, IHC (p), IF (p), IHC (fro), IF (cc) Hôte: Lapin Polyclonal unconjugated
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- Indications d'application
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Flow Cytometry: 1/50 - 1/200, Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Functional Assays.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: Endotoxin Level: less than 0.01EU/ug - Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- PBS, pH 7.4
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- -20 °C
- Stockage commentaire
- Store the antibody at -20 °C. Ship at 2 - 8 °C.
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- Antigène
- LAG3 (Lymphocyte-Activation Gene 3 (LAG3))
- Autre désignation
- CD223 / LAG3 (LAG3 Produits)
- Synonymes
- anticorps CD223, anticorps LAG-3, anticorps Ly66, anticorps lymphocyte activating 3, anticorps lymphocyte-activation gene 3, anticorps LAG3, anticorps Lag3
- Sujet
- CD223 is a 70kD activation-induced cell surface molecule. Murine CD223 is expressed on activated CD4 positive and CD8 positive alpha/beta T lymphocytes and a subset of natural killer (NK) cells. CD223 binds to MHC class II molecules with high affinity and is reported to negatively regulate T cell homeostasis and T cell expansion.Synonyms: FDC, LAG-3, Lymphocyte activation gene 3 protein
- ID gène
- 16768
- NCBI Accession
- NP_032505
- UniProt
- Q61790
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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