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CD8 anticorps (PE)

CD8 Reactivité: Rat FACS Hôte: Souris Monoclonal OX-8 PE
N° du produit ABIN120398
  • Antigène Voir toutes CD8 Anticorps
    CD8
    Reactivité
    • 236
    • 72
    • 25
    • 18
    • 13
    • 12
    • 10
    • 9
    • 9
    • 9
    • 8
    • 7
    • 7
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    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    Rat
    Hôte
    • 241
    • 53
    • 39
    Souris
    Clonalité
    • 277
    • 47
    • 2
    Monoclonal
    Conjugué
    • 98
    • 41
    • 32
    • 25
    • 12
    • 9
    • 6
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD8 est conjugé à/à la PE
    Application
    • 278
    • 66
    • 64
    • 47
    • 44
    • 44
    • 31
    • 19
    • 17
    • 14
    • 14
    • 14
    • 8
    • 5
    • 4
    • 3
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Specificité
    This antibody recognises the CD8 alpha cell surface antigen, expressed by a subset of T lymphocytes, most thymocytes and the majority of NK cells. Clone MRC OX-8 is suitable for use in in vitro blocking studies. We recommend the use of SM259A for this purpose. This clone has been described reacting with paraffin-embedded material following PLP Fixation (periodatelysine paraformaldehyde)
    Purification
    Affinity chromatography on Protein G
    Immunogène
    Rat thymocyte membrane glycoproteins. Spleen cells from immunised BALB/c mice were fused with cells of the mouse NS1 myeloma cell line.
    Clone
    OX-8
    Isotype
    IgG1
    Top Product
    Discover our top product CD8 Anticorps primaire
  • Indications d'application
    Flow Cytometry: Neat - 1/10, Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Reconstitution
    Restore with 1 mL distilled water
    Buffer
    PBS, pH 7.4 containing 0.09 % Sodium Azide and 1 % Bovine Serum Albumin
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    RT/4 °C/-20 °C
    Stockage commentaire
    Lyophilized: Store at 2-8 °C (preferably in a dessicator). Reconstituted: Aliquot and store at -20 °C.
  • Antigène
    CD8
    Autre désignation
    CD8 (CD8 Produits)
    Synonymes
    anticorps CD8, anticorps Leu2, anticorps MAL, anticorps p32, anticorps CD8a molecule, anticorps CD8A
    Sujet
    The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.Synonyms: CD8 alpha chain, CD8A, MAL, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2
    ID gène
    24930
    NCBI Accession
    NP_113726
    UniProt
    P07725
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