CD161 anticorps

N° du produit ABIN120522

Détail du produit anti-CD161 anticorps

Antigène: CD161 (KLRB1) (Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1))

Reactivité: Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD161 est non-conjugé

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Purification: Protein G affinity chromatography.

Immunogène: Purified splenic NK cells from the LEW rat strain.

Clone: 01-10-78

Isotype: IgG1

Information d'application

Indications d'application: Flow Cytometry: 1/50-1/100, use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Imunoprecipitation. Immunohistochemistry on frozen sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4 with 0.09 % sodium azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycle.

Stock: 4 °C/-20 °C

Stockage commentaire: Store lyophilized at 2-8 °C or -20 °C. After reconstitution, aliquot and freeze unused portions in volumes appropriate for single usage.

Détails sur CD161

Antigène: CD161 (KLRB1) (Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1))

Autre désignation: CD161 / KLRB1 (KLRB1 Produits)

Synonymes: anticorps NKR-P1, anticorps KLRB1, anticorps 4930431A04Rik, anticorps Gm4696, anticorps Klrb1g, anticorps Klrb6, anticorps Ly-55, anticorps Ly55, anticorps NKR-P1G, anticorps Nkrp-1e, anticorps Nkrp1g, anticorps CD161, anticorps CLEC5B, anticorps NKR, anticorps NKR-P1A, anticorps NKRP1A, anticorps hNKR-P1A, anticorps Klrb1d, anticorps Klrb1f, anticorps Nkr-p1e, anticorps killer cell lectin like receptor B1, anticorps killer cell lectin-like receptor subfamily B member 1, anticorps killer cell lectin-like receptor subfamily B, member 1, anticorps KLRB1, anticorps Klrb1

Sujet: Natural killer (NK) cells are lymphocytes that mediate cytotoxicity and secrete cytokines after immune stimulation. Several genes of the C-type lectin superfamily, including the rodent NKRP1 family of glycoproteins, are expressed by NK cells and may be involved in the regulation of NK cell function. The KLRB1 (CD161) protein contains an extracellular domain with several motifs characteristic of C type lectins, a transmembrane domain, and a cytoplasmic domain. The KLRB1 protein is classified as a type II membrane protein because it has an external C terminus. In mouse the NKRP1 family has three members, NKRP1A, B and C, whilst in human only one member has been identified. The human protein has received the designation CD161, and the mouse proteins have been referred to as CD161a, b and c. Engagement of CD161c has been reported to have activating function in NK cells, whilst engagement of CD161b is inhibitory.Synonyms: C-type lectin domain family 5 member B, CLEC5B, HNKR-P1a, Killer cell lectin-like receptor subfamily B member 1, NKRP1A, Natural killer cell surface protein P1A

ID gène: 3820

NCBI Accession: NP_002249

UniProt: Q12918