SIT1 anticorps (PE)

N° du produit ABIN120659

Détail du produit anti-SIT1 anticorps (PE)

Antigène: SIT1 (Signaling threshold Regulating Transmembrane Adaptor 1 (SIT1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SIT1 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Specificité: The antibody reacts with SHP2-interacting transmembrane adaptor protein (SIT) expressed exclusively in lymphoid organs.

Attributs du produit: Synonyms: Signaling threshold-regulating transmembrane adapter 1, SHP2-interacting transmembraneadapter protein, Suppression-inducing transmembrane adapter 1

Immunogène: Bacterially produced recombinant intracellular fragment of human SIT

Clone: SIT-01

Isotype: IgG1

Information d'application

Indications d'application: Suitable for Flow cytometry (1/50, intracellular staining). Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.1 mg/mL

Buffer: Phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2 % (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody at 2 - 8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur SIT1

Antigène: SIT1 (Signaling threshold Regulating Transmembrane Adaptor 1 (SIT1))

Autre désignation: SIT1 / SIT (SIT1 Produits)

Synonymes: anticorps SIT1, anticorps RP11-331F9.5, anticorps SIT, anticorps SIT-R, anticorps Sit, anticorps signaling threshold regulating transmembrane adaptor 1, anticorps suppression inducing transmembrane adaptor 1, anticorps SIT1, anticorps Sit1

Sujet: SIT (SHP2-interacting transmembrane adaptor protein) is expressed exclusively in lymphoid organs and acts either as a positive or as a negative regulatory element in T cell activation and in T cell development. Binding to Grb2 plays a pivotal role in signal transduction. Hubener et al. (2001) determined that the SIT gene contains 5 exons and spans 1.8 kb of genomic DNA. The SIT promoter demonstrated strong transcriptional activity and potential binding sites for both ubiquitous and lymphoid-specific transcription factors.Synonyms: SHP2-interacting transmembrane adapter protein, Signaling threshold-regulating transmembrane adapter 1, Suppression-inducing transmembrane adapter 1

ID gène: 27240

UniProt: Q9Y3P8