KRT8 anticorps

N° du produit ABIN120663

Cité dans 1 publication. Cet anticorps anti-KRT8 Monoclonal Souris (Clone C-43) (ABIN120663) détecte spécifiquement KRT8 dans WB, IF, IHC (p) et IP. L’anticorps est réactif avec des échantillons de Humain, Boeuf (Vache), Lapin, Porc et Mouton.

Aperçu rapide pour KRT8 anticorps (ABIN120663)

Antigène: KRT8 (Keratin 8 (KRT8))

Reactivité: Humain, Boeuf (Vache), Lapin, Porc, Mouton

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp KRT8 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)

Clone: C-43

Détail du produit anti-KRT8 anticorps

Specificité: The antibody C-43 reacts with Cytokeratin 8 (52.5 kDa).

Purification: Affinity Chromatography on Protein A

Immunogène: Cytoskeleton preparation from HeLa human cervix carcinoma cell line

Isotype: IgG1

Information d'application

Indications d'application: Immunoprecipitation. Western Blot. Immunocytochemistry. Immunohistochemistry (Paraffin): 20 m g/mL. Positive tissue: prostate.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.4, 15 mM Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

Date de péremption: 12 months

Références pour anticorps anti-KRT8 (ABIN120663)

Bártek, Vojt?sek, Stasková, Bártková, Kerekés, Rejthar, Kovarík: "A series of 14 new monoclonal antibodies to keratins: characterization and value in diagnostic histopathology." dans: The Journal of pathology, Vol. 164, Issue 3, pp. 215-24, (1991) (PubMed).

Détails sur KRT8

Antigène: KRT8 (Keratin 8 (KRT8))

Autre désignation: Cytokeratin 8

Sujet: Cytokeratins are a subfamily of intermediate filaments and characterized by remarkable biochemical diversity. Cytokeratins are represented in epithelial tissues by at least 20 different polypeptides, molecular weight between 40 kDa and 68 kDa. The individual cytokeratin polypeptides are designated 1 to 20 and divided into the type I (acidic cytokeratins 9-20) and type II (basic to neutral cytokeratins 1-8) families. Cytokeratin 8 belongs to the type B (basic) subfamily of high molecular weight keratins and exists in combination with cytokeratin 18. Cytokeratin 8 is primarily found in the non squamous epithelia and is present in majority of adenocarcinomas and ductal carcinomas. It is absent in squamous cell carcinomas. Hepatocellular carcinomas are defined by the use of antibodies that recognize only cytokeratin polypeptides 8 and 18.Synonyms: CK8, CYK8, Cytokeratin endo A, Cytokeratin-8, K8, KRT8, Keratin, Keratin-8, type II cytoskeletal 8

Poids moléculaire: 52.5 kDa

ID gène: 3856

UniProt: P05787