CD52 anticorps
Aperçu rapide pour CD52 anticorps (ABIN120666)
Antigène
Voir toutes CD52 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- This antibody Clone HI186 reacts with CD52, a 25-29 kDa glycoprotein containing a large N-linked carbohydrate moiety. Mature CD52 Molecule is actually much smaller (approx. 8-9 kDa).
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Réactivité croisée (Details)
- Species reactivity (tested):Human.
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Purification
- Protein A Chromatography
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Immunogène
- Human tonsil
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Isotype
- IgG2b
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Indications d'application
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Flow cytometry: use 5 μL of neat antibody to label 10^6 cells. Immunohistochemistry on frozen and paraffin embedded sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS, pH ~7.4, 15 mM Sodium Azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
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Store the antibody at 2-8 °C for up to one month or at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch. -
Date de péremption
- 12 months
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- CD52
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Autre désignation
- CD52 / CAMPATH-1
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Sujet
- CD52 (CAMPATH-1, HE5) is a highly glycosylated GPI-anchored 21-28 kDa glycopeptide which is present at high levels on lymphocytes, macrophages, epithelial cells of male reproductive tract and mature sperm. Its 12-amino acid beckbone carries a complex N-linked carbohydrate moiety, which differs between sperm and leukocyte CD52, as well as the GPI anchor does. CD52 can be acquired by sperm cells from seminal plasma, where it is released by epithelial cells. Although CD52 is not an essential T-cell costimulator, its triggering results in activation of normal human T cells. CD52 is a very good target for antibody/complement-mediated cell lysis.Synonyms: CDw52, Cambridge pathology 1 antigen, Epididymal secretory protein E5, HE5
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ID gène
- 1043
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UniProt
- P31358
Antigène
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