CD52 anticorps

N° du produit ABIN120666

Détail du produit anti-CD52 anticorps

Antigène: CD52

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD52 est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificité: This antibody Clone HI186 reacts with CD52, a 25-29 kDa glycoprotein containing a large N-linked carbohydrate moiety. Mature CD52 Molecule is actually much smaller (approx. 8-9 kDa).

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Protein A Chromatography

Immunogène: Human tonsil

Clone: HI186

Isotype: IgG2b

Information d'application

Indications d'application: Flow cytometry: use 5 μL of neat antibody to label 10^6 cells. Immunohistochemistry on frozen and paraffin embedded sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, pH ~7.4, 15 mM Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 2-8 °C for up to one month or at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

Date de péremption: 12 months

Détails sur CD52

Antigène: CD52

Autre désignation: CD52 / CAMPATH-1 (CD52 Produits)

Synonymes: anticorps CD52, anticorps AI463198, anticorps B7, anticorps B7-Ag, anticorps CAMPATH-1, anticorps CLS1, anticorps MB7, anticorps CDW52, anticorps CE5, anticorps CD52 molecule, anticorps CD52 antigen, anticorps CD52, anticorps Cd52

Sujet: CD52 (CAMPATH-1, HE5) is a highly glycosylated GPI-anchored 21-28 kDa glycopeptide which is present at high levels on lymphocytes, macrophages, epithelial cells of male reproductive tract and mature sperm. Its 12-amino acid beckbone carries a complex N-linked carbohydrate moiety, which differs between sperm and leukocyte CD52, as well as the GPI anchor does. CD52 can be acquired by sperm cells from seminal plasma, where it is released by epithelial cells. Although CD52 is not an essential T-cell costimulator, its triggering results in activation of normal human T cells. CD52 is a very good target for antibody/complement-mediated cell lysis.Synonyms: CDw52, Cambridge pathology 1 antigen, Epididymal secretory protein E5, HE5

ID gène: 1043

UniProt: P31358