CD1a anticorps (FITC)

N° du produit ABIN120677

Détail du produit anti-CD1a anticorps (FITC)

Antigène: CD1a

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD1a est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Specificité: The antibody reacts with CD1a (T6), a 49 KDa polypeptide associated with, b2-microglobulin expressed on cortical thymocytes (strongly), Langerhans cells, dendritic cells and some T cell leukemias and lymphomas. The antibody does not react with peripheral blood T and B lymphocytes, monocytes, granulocytes, platelets and erythrocytes.

Immunogène: Human thymocytes

Clone: HI149

Isotype: IgG1

Information d'application

Indications d'application: Flow Cytometry analysis of human cells using 20 μL reagent / 100 mLof whole blood or 10^6 cells in a suspension.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2 % (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody at 2 - 8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
Shelf Life: one year from despatch.

Date de péremption: 12 months

Détails sur CD1a

Antigène: CD1a

Autre désignation: CD1a (CD1a Produits)

Synonymes: anticorps CD1, anticorps FCB6, anticorps HTA1, anticorps R4, anticorps T6, anticorps CD1A, anticorps CD1a molecule, anticorps CD1 antigen, anticorps T-cell surface glycoprotein CD1a, anticorps CD1A, anticorps CD1.1, anticorps LOC100156095, anticorps LOC101111409

Sujet: CD1a, together with CD1b and c, belongs to group 1 of CD1 glycoproteins. These proteins serve as antigen-presenting molecules for a subset of T cells that responds to specific lipids and glycolipids found in the cell walls of bacterial pathogens or self-glycolipid antigens such as gangliosides, and they have also roles in antiviral immunity. Unlike CD1b, CD1a is excluded from late endosomal compartments and instead traffics independently in the recycling pathway of the early endocytic system, and CD1a antigen presentation is independent upon vesicular acidification.Synonyms: T-cell surface antigen T6/Leu-6, T-cell surface glycoprotein CD1a, T6/Leu-6, hTa1, hTa1 thymocyte antigen

UniProt: P06126

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process