MHC Class I RT1.Aa alpha-Chain (RT1.AA) anticorps

N° du produit ABIN120718

Détail du produit

Antigène: MHC Class I RT1.Aa alpha-Chain (RT1.AA)

Reactivité: Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Inconjugué

Application: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP)

Purification: Protein G Chromotraphy

Immunogène: Rat spleen membrane glycoproteins depleted of Ia-A antigens. Donor: BALB/c spleen. Fusion Partner: X63 Ag8.653

Clone: OX-18

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS

Agent conservateur: Azide free

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. Handle under aseptic conditions.
Shelf Life: one year from despatch.

Date de péremption: 12 months

Détail du antigène

Antigène: MHC Class I RT1.Aa alpha-Chain (RT1.AA)

Autre désignation: MHC Class I (RT1Aa) (RT1.AA Produits)

Synonymes: anticorps RTA, anticorps Rt1.aa, anticorps RT1 class I, locus A, anticorps RT1-A

Sujet: MHC Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. MHC class I antigens are heterodimers consisting of one alpha chain (44 kDa) with beta 2 microglobulin (11.5 kDa). The antigen is expressed by all somatic cells at varying levels. MHC Class I molecules are expressed on most nucleated cells where they present endogenously synthesized antigenic peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells. Fibroblasts or neurons however only show a low level of antigen.Synonyms: RT1 class I histocompatibility antigen AA alpha chain