MHC Class I RT1.Aa alpha-Chain (RT1.AA) anticorps
Aperçu rapide pour MHC Class I RT1.Aa alpha-Chain (RT1.AA) anticorps (ABIN120718)
Antigène
Voir toutes MHC Class I RT1.Aa alpha-Chain (RT1.AA) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Purification
- Protein G Chromotraphy
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Immunogène
- Rat spleen membrane glycoproteins depleted of Ia-A antigens. Donor: BALB/c spleen. Fusion Partner: X63 Ag8.653
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Isotype
- IgG1
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS
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Agent conservateur
- Azide free
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Stock
- 4 °C/-20 °C
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Stockage commentaire
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. Handle under aseptic conditions.
Shelf Life: one year from despatch. -
Date de péremption
- 12 months
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- MHC Class I RT1.Aa alpha-Chain (RT1.AA)
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Autre désignation
- MHC Class I (RT1Aa)
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Sujet
- MHC Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. MHC class I antigens are heterodimers consisting of one alpha chain (44 kDa) with beta 2 microglobulin (11.5 kDa). The antigen is expressed by all somatic cells at varying levels. MHC Class I molecules are expressed on most nucleated cells where they present endogenously synthesized antigenic peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells. Fibroblasts or neurons however only show a low level of antigen.Synonyms: RT1 class I histocompatibility antigen AA alpha chain
Antigène
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