CD235a/GYPA anticorps (N-Term)

N° du produit ABIN120751

Détail du produit anti-CD235a/GYPA anticorps

Antigène: CD235a/GYPA (GYPA) (Glycophorin A (GYPA))

Épitope: N-Term

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD235a/GYPA est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Aggregation (AGG), Haemagglutination (H)

Specificité: This antibody clone HIR2 recognizes N-terminal portion of glycophorin A (and weakly of glycophorin B). Its antigen is expressed on early erythroblasts, late erythroblasts, erythroblasts, mature erythrocytes and the cells of erythroid cell lines K562 and HEL, but not on all other cells.

Purification: Protein G chromatography

Immunogène: Synthetic peptide (Human, N-terminal)

Clone: HIR2

Isotype: IgG2b

Information d'application

Indications d'application: Flow cytometry: This HIR2 antibody has been tested by flow cytometric analysis of human peripheral blood leukocytes and cell agglutination assay and can be used at approximately 0.1 μg per million cells. Immunohistochemistry (frozen sections). Agglutination: Clone HIR2 agglutinates untreated RBCs but it failes to agglutinate papain- treated cells.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS with 15 mM sodium azide, approx. pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

Date de péremption: 12 months

Références pour anticorps anti-CD235a/GYPA (ABIN120751)

Moles, Galiano, Gomes, Quiliano, Teixeira, Aldana, Gomes, Fernàndez-Busquets: "ImmunoPEGliposomes for the targeted delivery of novel lipophilic drugs to red blood cells in a falciparum malaria murine model." dans: Biomaterials, Vol. 145, pp. 178-191, (2018) (PubMed).

Détails sur CD235a/GYPA

Antigène: CD235a/GYPA (GYPA) (Glycophorin A (GYPA))

Autre désignation: CD235a / GYPA (GYPA Produits)

Synonymes: anticorps GYPA, anticorps gpa, anticorps AI853584, anticorps CD235a, anticorps GPA, anticorps GPErik, anticorps GPSAT, anticorps HGpMiV, anticorps HGpMiXI, anticorps HGpSta(C), anticorps MN, anticorps MNS, anticorps PAS-2, anticorps glycophorin A (MNS blood group), anticorps glycophorin A, anticorps GYPA, anticorps Gypa

Sujet: CD235a (Glycophorin A, GPA) is a transmembrane sialoglycoprotein expressed on erythrocytes and their precursors. Similarly to glycophorin B (GPB), these molecules provide the cells with a large mucin-like surface, which minimalizes aggregation between erythrocytes in the circulation. GPA is the carrier of blood group M and N specificities, while GPB accounts for S, s and U specificities. CD235a is a receptor of Hsa, an Streptococcus adhesin.Synonyms: GPA, Glycophorin-A, MN sialoglycoprotein, PAS-2, Sialoglycoprotein alpha

ID gène: 2993

UniProt: P02724

Pathways: Maintenance of Protein Location