TUBA1B anticorps

N° du produit ABIN121117

Cet anticorps Rat Monoclonal détecte spécifiquement TUBA1B dans WB, IF, IHC (p), IHC (fro), IP, EIA et RIA. Il présente une réactivité envers Humain, Souris, Rat, Avian, Mammifères et Saccharomyces cerevisiae et a été mentionné dans 4+ publications.

Aperçu rapide pour TUBA1B anticorps (ABIN121117)

Antigène: TUBA1B (Tubulin, alpha 1B (TUBA1B))

Reactivité: Humain, Souris, Rat, Avian, Mammifères, Saccharomyces cerevisiae

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp TUBA1B est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Enzyme Immunoassay (EIA), Radioimmunoassay (RIA)

Clone: YOL1-34

Détail du produit anti-TUBA1B anticorps

Specificité: SM568P specifically recognizes the alpha subunit of Tubulin. The reactivity pattern is similar to that seen with Clone YL1/2 (cat.-No SM2202P). This antibody is routinely tested in ELISA on Tubulin.

Purification: Affinity Chromatography on Protein G

Immunogène: Yeast tubulin

Isotype: IgG2a

Information d'application

Indications d'application: Immunohistochemistry on Frozen Sections. ELISA: 10 μg/ul as detecting antibody. RIA. Western blotting.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This antibody is routinely tested in Elisa on Tubulin.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

Date de péremption: 12 months

Références pour anticorps anti-TUBA1B (ABIN121117)

Lang, Grether-Beck, Singh, Kuck, Jakob, Kefalas, Altinoluk-Hambüchen, Graffmann, Schneider, Lindecke, Brenden, Felsner, Ezzahoini, Marini, Weinhold, Vierkötter, Tigges, Schmidt, Stühler, Köhrer et al.: "MicroRNA-15b regulates mitochondrial ROS production and the senescence-associated secretory phenotype through sirtuin 4/SIRT4. ..." dans: Aging, Vol. 8, Issue 3, pp. 484-505, (2016) (PubMed).

Takeyama, Yuki, Tokuhara, Oroku, Mejima, Kurokawa, Kuroda, Kodama, Nagai, Ueda, Kiyono: "Oral rice-based vaccine induces passive and active immunity against enterotoxigenic E. coli-mediated diarrhea in pigs." dans: Vaccine, Vol. 33, Issue 39, pp. 5204-11, (2016) (PubMed).

Kessler, Reich, Jahn, Tolosa, Beck, Kalbacher, Overkleeft, Schempp, Driessen: "Human cytomegalovirus infection interferes with major histocompatibility complex type II maturation and endocytic proteases in dendritic cells at multiple levels." dans: The Journal of general virology, Vol. 89, Issue Pt 10, pp. 2427-36, (2008) (PubMed).

Valenta, Lukas, Doubravska, Fafilek, Korinek: "HIC1 attenuates Wnt signaling by recruitment of TCF-4 and beta-catenin to the nuclear bodies." dans: The EMBO journal, Vol. 25, Issue 11, pp. 2326-37, (2006) (PubMed).

Détails sur TUBA1B

Antigène: TUBA1B (Tubulin, alpha 1B (TUBA1B))

Autre désignation: alpha Tubulin / TUBA1B

Sujet: Microtubules are involved in a wide variety of cellular activities ranging from mitosis and transport events to cell movement and the maintenance of cell shape. Tubulin itself is a globular protein consisting of two polypeptides (alpha and beta tubulin). Alpha and beta tubulin dimers are assembled to 13 protofilaments that form a microtubule of 22-nm diameter. Tyrosine ligase adds a C-terminal tyrosine to monomeric alpha tubulin. Assembled microtubules can again be detyrosinated by a cytoskeleton-associated carboxypeptidase. Detyrosinated alpha tubulin is referred to as Glu-tubulin. Another post-translational modification of detyrosinated alpha tubulin is C-terminal polyglutamylation, which is characteristic of microtubules in neuronal cells and the mitotic spindle.Synonyms: Alpha-tubulin ubiquitous, Tubulin K-alpha-1, Tubulin alpha-1B chain, Tubulin alpha-ubiquitous chain

Pathways: Dynamique des Microtubules, M Phase