DC-SIGN/CD209 anticorps (AA 277-293)

N° du produit ABIN121620

Cet anticorps anti-DC-SIGN/CD209 Polyclonal Lapin (ABIN121620) détecte spécifiquement DC-SIGN/CD209 dans WB, IF et IHC (fro). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour DC-SIGN/CD209 anticorps (AA 277-293) (ABIN121620)

Antigène: DC-SIGN/CD209 (CD209) (CD209)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DC-SIGN/CD209 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-DC-SIGN/CD209 anticorps

Épitope: AA 277-293

Specificité: This antibody recognizes an epitope within the extracellular domain of CD209/DC-SIGN.

Purification: Affinity Chromatography

Immunogène: Synthetic peptide corresponding to amino acids 277-293 of human DC-SIGN

Information d'application

Indications d'application: Western Blot: 1 μg/mL - 2 μg/mL, This antibody detects a band of approximately 44 kD by western blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS, 0.02 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

Date de péremption: 12 months

Détails sur DC-SIGN/CD209

Antigène: DC-SIGN/CD209 (CD209) (CD209)

Autre désignation: CD209 / DC-SIGN

Sujet: Dendritic cells (DCs) that control immune responses were recently found to capture and transport HIV from the mucosal area to remote lymph nodes, where DCs hand over HIV to CD4+ T lymphocytes. DCs also amplify the amount of virus and extend the duration of viral infectivity. Multiple strains of HIV1, HIV2 and SIV bind to DCs via DCSIGN. ICAM3 is the natural ligand for DC-SIGN. A DC-SIGN homologue (termed CD299, DC-SIGNR, L-SIGN and DCSIGN2) was identified recently. DC-SIGN forms a novel gene family with DC-SIGNR and many alternatively spliced isoforms of DC-SIGN and DC-SIGNR. The expression of DC-SIGN was found in mucosal tissues including placenta, small intestine, and rectum.Synonyms: C-type lectin domain family 4 member L, CLEC4L, DC-SIGN1, DCSIGN, DCSIGN1, Dendritic Cell Marker, Dendritic cell-specific ICAM-3-grabbing non-integrin 1

UniProt: Q9NNX6