Calcitonin Receptor anticorps

N° du produit ABIN121621

Cet anticorps Lapin Polyclonal détecte spécifiquement Calcitonin Receptor dans WB, IHC (p) et EIA. Il présente une réactivité envers Humain, Rat et Souris et a été mentionné dans 1 publication.

Aperçu rapide pour Calcitonin Receptor anticorps (ABIN121621)

Antigène: Calcitonin Receptor (CALCR)

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Calcitonin Receptor est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-Calcitonin Receptor anticorps

Specificité: SP1338P reacts with the Calcitonin Receptor. It recognises an epitope within the cytoplasmic domain that is common to both C1a and C1b Rat isoforms.

Réactivité croisée (Details): Species reactivity (tested):Rat. Cross reacts with Mouse and Human.

Purification: Affinity Chromatography on Protein A.

Immunogène: Synthetic peptide derived from sequence of rat calcitonin receptor

Information d'application

Indications d'application: Immunohistochemistry on paraffin embedded tissues (1:10 - 1:100): The use of 4 % paraformaldehyde fixation rather than formalin fixation is recommended. Does not require protein digestion pre-treatment nor antigen retrieval using heat prior to staining of paraffin embedded sections. Suitable positive control: Kidney, cultered osteoclasts. A sensitive detection system is also recommended, e.g. a catalysed signal amplification system). ELISA (1:10,000). Western blot using reducing conditions.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

Date de péremption: 12 months

Références pour anticorps anti-Calcitonin Receptor (ABIN121621)

Segovia-Silvestre, Bonnefond, Sondergaard, Christensen, Karsdal, Bay-Jensen: "Identification of the calcitonin receptor in osteoarthritic chondrocytes." dans: BMC research notes, Vol. 4, pp. 407, (2011) (PubMed).

Détails sur Calcitonin Receptor

Antigène: Calcitonin Receptor (CALCR)

Autre désignation: Calcitonin Receptor

Sujet: Calcitonin Receptor is a seven transmembrane domain cell surface protein which is coupled to G protein messenger systems. Calcitonin receptor is expressed in kidney, central and peripheral nervous systems and in osteoclasts. It is also expressed in a number of tissues during the development of the embyro and may be important in foetal morphogenesis.Synonyms: CALCR, CT-R, CTR

ID gène: 116506

UniProt: P32214

Pathways: cAMP Metabolic Process