Collagen Type I anticorps
Aperçu rapide pour Collagen Type I anticorps (ABIN121921)
Antigène
Voir toutes Collagen Type I (COL1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- This antibody recognises human Type 1 collagen. It has been cross-adsorbed against collagen types II, III, IV, V and VI. Results from ELISA demonstrate < 10 % cross-reactivity with other collagen types.
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Attributs du produit
- Synonyms: COL1A1, COL1A2, Alpha-1 type I collagen, Alpha-2 type I collagen
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Purification
- Affinity chromatography
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Immunogène
- Human type 1 collagen
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Indications d'application
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Immunohistochemistry on frozen sections (1: 10 - 1: 20). ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 0.4 mg/mL
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Buffer
- 100 mM Borate buffered saline, pH 8.0, without preservatives and stabilizers.
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Agent conservateur
- Without preservative
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Stock
- -20 °C
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Stockage commentaire
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Store (in aliquots, undiluted) at -20 °C. Avoid repeated freezing and thawing. Should thisproduct contain a precipitate we recommend microcentrifugation before use.
Shelf life: one year from despatch. -
Date de péremption
- 12 months
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- Collagen Type I (COL1) (Collagen, Type I (COL1))
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Autre désignation
- Collagen Type I
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Sujet
- Collagens are highly conserved throughout evolution and are characterised by an uninterrupted "Glycine X Y" triplet repeat that is a necessary part of the triple helical structure. Type I collagen (95 kDa) is found in bone, cornea, skin and tendon. Mutations in the encoding gene are associated with osteogenesis imperfecta, Ehlers Danlos syndrome, and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for Platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor.Synonyms: Alpha-1 type I collagen, Alpha-2 type I collagen, COL1A1, COL1A2
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ID gène
- 1277
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UniProt
- P02452
Antigène
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