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Collagen Type I anticorps

Cet anticorps Chèvre Polyclonal détecte spécifiquement Collagen Type I dans IHC (fro) et EIA. Il présente une réactivité envers Humain.
N° du produit ABIN121921

Aperçu rapide pour Collagen Type I anticorps (ABIN121921)

Antigène

Voir toutes Collagen Type I (COL1) Anticorps
Collagen Type I (COL1) (Collagen, Type I (COL1))

Reactivité

  • 98
  • 61
  • 56
  • 18
  • 18
  • 17
  • 15
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Humain

Hôte

  • 68
  • 38
  • 12
Chèvre

Clonalité

  • 80
  • 38
Polyclonal

Conjugué

  • 59
  • 15
  • 6
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
Cet anticorp Collagen Type I est non-conjugé

Application

  • 78
  • 41
  • 38
  • 34
  • 30
  • 27
  • 27
  • 23
  • 18
  • 17
  • 17
  • 13
  • 11
  • 5
  • 4
  • 3
  • 1
Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)
  • Specificité

    This antibody recognises human Type 1 collagen. It has been cross-adsorbed against collagen types II, III, IV, V and VI. Results from ELISA demonstrate < 10 % cross-reactivity with other collagen types.

    Attributs du produit

    Synonyms: COL1A1, COL1A2, Alpha-1 type I collagen, Alpha-2 type I collagen

    Purification

    Affinity chromatography

    Immunogène

    Human type 1 collagen
  • Indications d'application

    Immunohistochemistry on frozen sections (1: 10 - 1: 20). ELISA.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Concentration

    0.4 mg/mL

    Buffer

    100 mM Borate buffered saline, pH 8.0, without preservatives and stabilizers.

    Agent conservateur

    Without preservative

    Stock

    -20 °C

    Stockage commentaire

    Store (in aliquots, undiluted) at -20 °C. Avoid repeated freezing and thawing. Should thisproduct contain a precipitate we recommend microcentrifugation before use.
    Shelf life: one year from despatch.

    Date de péremption

    12 months
  • Antigène

    Collagen Type I (COL1) (Collagen, Type I (COL1))

    Autre désignation

    Collagen Type I

    Sujet

    Collagens are highly conserved throughout evolution and are characterised by an uninterrupted "Glycine X Y" triplet repeat that is a necessary part of the triple helical structure. Type I collagen (95 kDa) is found in bone, cornea, skin and tendon. Mutations in the encoding gene are associated with osteogenesis imperfecta, Ehlers Danlos syndrome, and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for Platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor.Synonyms: Alpha-1 type I collagen, Alpha-2 type I collagen, COL1A1, COL1A2

    ID gène

    1277

    UniProt

    P02452
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