LPAR5 anticorps

N° du produit ABIN122193

Cet anticorps anti-LPAR5 Polyclonal Lapin (ABIN122193) détecte spécifiquement LPAR5 dans IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour LPAR5 anticorps (ABIN122193)

Antigène: LPAR5 (Lysophosphatidic Acid Receptor 5 (LPAR5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LPAR5 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-LPAR5 anticorps

Specificité: Reacts to G Protein-Coupled Receptor GPR92/GPR93 (Family: GPCR, Subfamily: Orphan-A)

Purification: Peptide immunogen affinity column

Immunogène: Synthetic peptide - KLH conjugated

Information d'application

Indications d'application: Immunohistochemistry with formalin fixed paraffin embedded tissues: 1.5 -4 μg/mL (for details please see Protocols below).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-80 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

Date de péremption: 12 months

Détails sur LPAR5

Antigène: LPAR5 (Lysophosphatidic Acid Receptor 5 (LPAR5))

Autre désignation: LPAR5 / GPR92 / GPR93

Sujet: GPR92/GPR93 binds and is activated by compounds based on the lysophosphatidic acid (LPA) backbone. The binding of LPA to GPR92 was of high affinity and led to an increase in both phosphoinositide hydrolysis and c-AMP production. GPR92 is atypical in that it has a low sequence homology with the classic LPA receptors (21-22 % ). The expression of GPR92 is mainly found in brain, testis, heart, placenta, spleen, lung, and gut. Notably, GPR92 is highly expressed in the lymphocyte compartment of the gastrointestinal tract. It is the most abundant GPCR that is activated by LPA found in the small intestinal intraepithelial CD8+ cytotoxic T cells.Synonyms: 93, G-protein coupled receptor 92, LPA receptor 5, LPA-5, Lysophosphatidic acid receptor 5

ID gène: 57121

UniProt: Q9H1C0