GNRHR anticorps

N° du produit ABIN122264

L’anticorps anti-GNRHR Polyclonal Lapin est utilisé pour la détection de GNRHR dans des échantillons de Humain, Souris et Rat. Il a été validé pour IHC (p).

Aperçu rapide pour GNRHR anticorps (ABIN122264)

Antigène: GNRHR (Gonadotropin-Releasing Hormone Receptor (GNRHR))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GNRHR est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-GNRHR anticorps

Specificité: Reacts with Gonadotropin-Releasing Hormone Receptor (GnRHR) (family: GPCR, subfamily: Releasing hormone).

Purification: Peptide Immunogen Affinity Chromatography.

Immunogène: Synthetic peptide - KLH conjugated

Information d'application

Indications d'application: Immunohistochemistry with formalin fixed paraffin embedded tissues: 1-2 μg/mL Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C forlonger. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur GNRHR

Antigène: GNRHR (Gonadotropin-Releasing Hormone Receptor (GNRHR))

Autre désignation: GnRH Receptor / GNRHR

Sujet: GnRHR is a Releasing-Hormone Receptor activated by gonadotropin-releasing hormone (GnRH). This receptor plays a major role in the regulation of reproductive functions. It modulates the synthesis and secretion of gonadotropin hormones such as luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the pituitary. In turn, LH and FSH regulate the release of steroid hormones from the gonads. Mutations in GnRHR have been linked to hypogonadotropic hypogonadism, a condition characterized by absence or delayed puberty and retarded bone maturation. GnRHR has been reported to be expressed mostly in the pituitary gonadotropes and in reproductive organs, including ovary, placenta, prostate, testis, and uterus. It is also expressed in breast, heart, kidney, liver, skeletal muscle, and thymus. No human ESTs have been isolated for this receptor.Synonyms: GRHR, GnRH-R, Gonadotropin-releasing hormone receptor

ID gène: 2798

UniProt: P30968