GRM2 anticorps (N-Term)

N° du produit ABIN122313

Cet anticorps anti-GRM2 est un anticorps Lapin Polyclonal détectant GRM2 dans WB, IF et IHC (p). Adapté pour Humain, Rat, Souris, Boeuf (Vache) et Porc.

Aperçu rapide pour GRM2 anticorps (N-Term) (ABIN122313)

Antigène: GRM2 (Glutamate Receptor, Metabotropic 2 (GRM2))

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRM2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-GRM2 anticorps

Épitope: N-Term

Specificité: Reacts with Metabotropic Glutamate Receptor 2 (family: GPCR, subfamily: Metabotropic glutamate)

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat, Bovine, PigSpecies reactivity (tested):Human

Purification: Immunoaffinity Chromatography

Immunogène: Synthetic peptide - KLH conjugated

Information d'application

Indications d'application: Western Blot. Immunocytochemistry. Immunohistochemistry with formalin fixed paraffin embedded tissues: 5-10 μg/mL Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 to -80 °C forlonger. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur GRM2

Antigène: GRM2 (Glutamate Receptor, Metabotropic 2 (GRM2))

Autre désignation: mGluR2 / GRM2

Sujet: The Metabotropic Glutamate Receptor GRM2 binds L-glutamate and has been linked to the inhibition of the cyclic AMP signaling cascade. GRM2 is involved in mediating the suppression of neurotransmission and in synaptogenesis and synaptic stabilization. Glutamatergic neurotransmission plays a role in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. GRM2 has been reported in various regions of the human and animal brain, as well as in rat eye and spinal cord. ESTs have been isolated from brain and testis libraries. Caution: GLUR2 refers to Ionotropic Glutamate Receptor 2, not to Metabotropic Glutamate Receptor 2 (mGLUR2).Synonyms: GPRC1B, Metabotropic glutamate receptor 2

ID gène: 2912

UniProt: Q14416

Pathways: cAMP Metabolic Process, Dicarboxylic Acid Transport