GHRHR anticorps (C-Term)

N° du produit ABIN122454

Cet anticorps anti-GHRHR Polyclonal Lapin (ABIN122454) détecte spécifiquement GHRHR dans IHC (p). L’anticorps est réactif avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour GHRHR anticorps (C-Term) (ABIN122454)

Antigène: GHRHR (Growth Hormone Releasing Hormone Receptor (GHRHR))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GHRHR est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-GHRHR anticorps

Épitope: C-Term

Specificité: Reacts with Growth Hormone Releasing Hormone Receptor (family: GPCR, subfamily: Growth hormone releasing hormone)

Purification: Peptide Immunogen Affinity Chromatography.

Immunogène: Synthetic peptide - KLH conjugated

Information d'application

Indications d'application: Immunohistochemistry with formalin fixed paraffin embedded tissues: 16 μg/mL Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.7, containing 0.01 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C forlonger. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur GHRHR

Antigène: GHRHR (Growth Hormone Releasing Hormone Receptor (GHRHR))

Autre désignation: GHRH Receptor

Sujet: GHRHR, a Growth Hormone-Releasing Hormone Receptor, is involved in the proliferation and differentiation of somatotrophic pituitary cells and in disease. The GHRH receptor stimulates growth hormone (GH) secretion and synthesis in the pituitary. Mutations in this receptor cause either growth-hormone deficiency, resulting in dwarfism, or excessive production of the hormone, leading to gigantism. Four alternative splice variants have been identified that are tissue specific. GHRHR has been reported to be expressed primarily in the brain. ESTs have been isolated from brain and pituitary libraries.Synonyms: GHRHR, GRF receptor, GRFR, Growth hormone-releasing factor receptor, Growth hormone-releasing hormone receptor

ID gène: 2692

UniProt: Q02643

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Hormone Transport, Regulation of Intracellular Steroid Hormone Receptor Signaling, cAMP Metabolic Process