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TACR1 anticorps (C-Term)

Cet anticorps anti-TACR1 est un anticorps Lapin Polyclonal détectant TACR1 dans IHC (p). Adapté pour Humain, Rat, Souris, Chien, Cobaye, Boeuf (Vache), Cheval, Lapin et Hamster.
N° du produit ABIN122523

Aperçu rapide pour TACR1 anticorps (C-Term) (ABIN122523)

Antigène

Voir toutes TACR1 Anticorps
TACR1 (Tachykinin Receptor 1 (TACR1))

Reactivité

  • 61
  • 28
  • 20
  • 5
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Humain, Rat, Souris, Chien, Cobaye, Boeuf (Vache), Cheval, Lapin, Hamster

Hôte

  • 60
  • 8
  • 1
Lapin

Clonalité

  • 58
  • 11
Polyclonal

Conjugué

  • 45
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Cet anticorp TACR1 est non-conjugé

Application

  • 38
  • 22
  • 21
  • 9
  • 7
  • 6
  • 6
  • 6
  • 4
  • 3
  • 2
  • 1
  • 1
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Épitope

    • 7
    • 5
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Specificité

    This antibody detects Tachykinin receptor 1 (TACR1) at C-term. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except DTNB (44 %).

    Réactivité croisée (Details)

    Species reactivity (tested):Human

    Purification

    Immunoaffinity chromatography.

    Immunogène

    Synthetic peptide - KLH conjugated
  • Indications d'application

    Immunohistochemistry with formalin fixed paraffin embedded tissues: 1-40 μg/mL Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.

    Restrictions

    For Research Use only
  • Concentration

    1.0 mg/mL

    Buffer

    PBS containing 0.09 % Sodium azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C/-80 °C

    Stockage commentaire

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.

    Date de péremption

    12 months
  • Antigène

    TACR1 (Tachykinin Receptor 1 (TACR1))

    Sujet

    Tachykinin receptor 1, a member of the tachykinin receptor subfamily, is involved in the mediation of phosphatidylinositol metabolism by the tachykinin substance P, also referred to as neurokinin 1. It is associated with the management of depression, anxiety, and stress. It is also involved in regulating behavioral responses, neuronal survival, and cardiovascular and respiratory functions. The tachykinin receptor 1 is implicated in the progression of rheumatoid arthritis and osteoarthritis. Two variants of the tachykinin receptor 1 are produced by alternative splicing. Tachykinin receptor 1 has been reported primarily in brain, and in blood lymphocytes, nose, small intestine, and stomach. ESTs have been isolated from brain and spleen libraries.Synonyms: NK-1 receptor, NK-1R, NK1R, SPR, Substance-P receptor, TAC1R

    ID gène

    6869

    UniProt

    P25103

    Pathways

    Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour, Smooth Muscle Cell Migration
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