CD9 anticorps

N° du produit ABIN125680

Cet anticorps Souris Monoclonal détecte spécifiquement CD9 dans FACS, WB, IHC (p), Func et MS. Il présente une réactivité envers Humain et a été mentionné dans 2+ publications.

Aperçu rapide pour CD9 anticorps (ABIN125680)

Antigène: CD9

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD9 est non-conjugé

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Functional Studies (Func), Mass Spectrometry (MS)

Clone: MEM-61

Détail du produit anti-CD9 anticorps

Fonction: Anti-Hu CD9 Purified Azide Free

Specificité: The antibody MEM-61 recognizes an epitope on second extracellular domain (EC2) of CD9 antigen, a 24 kDa transmembrane protein expressed on platelets, monocytes, pre-B lymphocytes, granulocytes and activated T lymphocytes.

Réactivité croisée (Details): Human

Purification: Purified by protein-A affinity chromatography.

Pureté: > 95 % (by SDS-PAGE)

Immunogène: Pre-B cell line NALM-6.

Isotype: IgG1 kappa

Information d'application

Indications d'application: Functional application: The antibody MEM-61 induces FcγR-dependent platelet aggregation.
Flow cytometry: Recommended dilution: 1-4 μg/mL.
Western blotting: Recommended dilution: 2-4 μg/mL, non-reducing conditions.
Immunohistochemistry (paraffin sections): Recommended dilution: 10 μg/mL, positive tissue: prostate.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4

Agent conservateur: Azide free

Conseil sur la manipulation: Do not freeze.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Do not freeze.

Références pour anticorps anti-CD9 (ABIN125680)

Singh, Sugimoto, Dhawan, Harris: "Juxtacrine activation of EGFR regulates claudin expression and increases transepithelial resistance." dans: American journal of physiology. Cell physiology, Vol. 293, Issue 5, pp. C1660-8, (2007) (PubMed).

Stöckl, Majdic, Fischer, Maurer, Knapp: "Monomorphic molecules function as additional recognition structures on haptenated target cells for HLA-A1-restricted, hapten-specific CTL." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 167, Issue 5, pp. 2724-33, (2001) (PubMed).

Détails sur CD9

Antigène: CD9

Autre désignation: CD9

Sujet: CD9 Molecule,CD9 belongs to proteins of tetraspanin family that orchestrate cholesterol-associated tetraspanin-enriched signaling microdomains within the plasma membrane, forming complexes with each other as well as with integrins, membrane-anchored growth factors and other proteins. CD9 is involved in cell motility, osteoclastogenesis, neurite outgrowth, myotube formation, and sperm-egg fusion, plays roles in cell attachment and proliferation and is necessary for association of heterologous MHC II molecules on the dendritic cell plasma membrane which is important for effective T cell stimulation. CD9 is also considered as metastasis suppressor in solid tumors.,MIC3, MRP-1, BTCC-1, DRAP-27, TSPAN29, BA2

ID gène: 928

UniProt: P21926

Pathways: Response to Water Deprivation, Cell-Cell Junction Organization