CXCR6 anticorps (AA 11-25)

N° du produit ABIN126328

Détail du produit anti-CXCR6 anticorps

Antigène: CXCR6 (Chemokine (C-X-C Motif) Receptor 6 (CXCR6))

Épitope: AA 11-25

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CXCR6 est non-conjugé

Application: Western Blotting (WB)

Specificité: SP1286P recognises the orphan G protein-coupled chemokine receptor CXCR6, also known as CDw186. CXCR6 has been identified as a co-receptor for simian immunodeficiency virus (SIV), HIV-2 and HIV-1. Lymphoid tissues and activated peripheral blood lymphocytes express CXCR6 mRNA.

Purification: Affinity purified immunoglobulin fraction

Immunogène: Peptide corresponding to aa 11 to 25 of human CXCR6/CDw186 (NT)

Isotype: IgG

Information d'application

Indications d'application: Western blot (1/500).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C or at -20 °C if preferred. Avoid repeated freezing and thawing.
Shelf Life: One year from despatch.

Date de péremption: 12 months

Détails sur CXCR6

Antigène: CXCR6 (Chemokine (C-X-C Motif) Receptor 6 (CXCR6))

Autre désignation: CD186 / CXCR6 (CXCR6 Produits)

Synonymes: anticorps BONZO, anticorps CD186, anticorps STRL33, anticorps TYMSTR, anticorps BB217514, anticorps C-X-C motif chemokine receptor 6, anticorps chemokine (C-X-C motif) receptor 6 L homeolog, anticorps chemokine (C-X-C motif) receptor 6, anticorps CXCR6, anticorps cxcr6.L, anticorps Cxcr6

Sujet: Human Immunodeficiency Virus (HIV) and Simian Immunodeficiency Virus (SIV) require coreceptors to enter and infect target cells. They are dependent upon an interaction between the viral envelope glycoprotein with T cell antigen T4 (CD4) and a G protein coupled receptor (GPCR). HIV1 infection relies upon interaction with a chemokine receptor, usually chemokine (C-C) receptor 5 (CCR5). During progression of the infection, the virus tends to rely upon chemokine (C-X-C) receptor 4 (CXCR4). SIV also utilizes CCR5 in the early stages of infection, but during progression it tends to rely on two orphan GPCR's named chemokine (C-X-C) receptor 6 (Bonzo) and G protein coupled receptor 15 (BOB/GRP15). Bonzo mRNA expression has been localized to lymphoid tissues and activated peripheral blood lymphocytes.Synonyms: BONZO, CDw186, CXC-R6, CXCR-6, G-protein coupled receptor STRL33, G-protein coupled receptor bonzo, STRL33, TYMSTR

ID gène: 10663

UniProt: O00574