BOK anticorps

N° du produit ABIN126989

L’anticorps anti-BOK Polyclonal Lapin est utilisé pour la détection de BOK dans des échantillons de Rat. Il a été validé pour WB.

Aperçu rapide pour BOK anticorps (ABIN126989)

Antigène: BOK (BCL2-Related Ovarian Killer (BOK))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BOK est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-BOK anticorps

Specificité: This antibody reacts to Bok.

Purification: Affinity purified

Immunogène: Synthetic peptide surrounding amino acid 44 of rat BOK.

Information d'application

Indications d'application: Western Blot: 0.5-4g/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.2 mg/mL

Buffer: PBS, pH 7.2, containing 50 % glycerol, 1 % BSA, 0.02 % thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C/-80 °C

Stockage commentaire: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.

Détails sur BOK

Antigène: BOK (BCL2-Related Ovarian Killer (BOK))

Autre désignation: BOK / BCL2L9

Sujet: Bok (Bcl-2-related ovarian killer) is a pro-apoptotic Bcl-2 family protein identified in the ovary based on its dimerization with the anti-apoptotic protein Mcl-1. In addition to the Bcl-2 homology (BH) domains 1 and 2 and the transmembrane sequence, Bok also has a BH3 domain believed to be important for dimerization with selective anti-apoptotic Bcl-2 proteins and cell killing. Bok interacts strongly with some (Mcl-1, BHRF1, and Bfl-1) but not other (Bcl-2, Bcl-xL, and Bcl-w) anti-apoptotic members. In addition, cell killing induced by Bok was suppressed following coexpression with Mcl-1 and BHRF1, but not with Bcl-2, further indicating that Bok heterodimerized only with selective anti-apoptotic Bcl-2 proteins. Bok was highly expressed in the ovary, testis and uterus.Synonyms: Bcl-2-like protein 9, Bcl-2-related ovarian killer protein, Bcl2-L-9, Hbok

ID gène: 29884

NCBI Accession: NP_059008

UniProt: Q792S6

Pathways: Positive Regulation of Endopeptidase Activity