BOK anticorps
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- Antigène Voir toutes BOK Anticorps
- BOK (BCL2-Related Ovarian Killer (BOK))
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Reactivité
- Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp BOK est non-conjugé
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Application
- Western Blotting (WB)
- Specificité
- This antibody reacts to Bok.
- Purification
- Affinity purified
- Immunogène
- Synthetic peptide surrounding amino acid 44 of rat BOK.
- Top Product
- Discover our top product BOK Anticorps primaire
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- Indications d'application
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Western Blot: 0.5-4g/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 0.2 mg/mL
- Buffer
- PBS, pH 7.2, containing 50 % glycerol, 1 % BSA, 0.02 % thimerosal
- Agent conservateur
- Thimerosal (Merthiolate)
- Précaution d'utilisation
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- -20 °C/-80 °C
- Stockage commentaire
- Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
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- Antigène
- BOK (BCL2-Related Ovarian Killer (BOK))
- Autre désignation
- BOK / BCL2L9 (BOK Produits)
- Synonymes
- anticorps BOK, anticorps bok, anticorps zgc:100979, anticorps zgc:64041, anticorps BCL2L9, anticorps BOKL, anticorps Bok-BH3, anticorps AI847676, anticorps AU021146, anticorps matador, anticorps mtd, anticorps BOK, BCL2 family apoptosis regulator, anticorps BCL2-related ovarian killer a, anticorps BCL2-related ovarian killer b, anticorps BCL2-related ovarian killer, anticorps BOK, anticorps boka, anticorps bokb, anticorps Bok
- Sujet
- Bok (Bcl-2-related ovarian killer) is a pro-apoptotic Bcl-2 family protein identified in the ovary based on its dimerization with the anti-apoptotic protein Mcl-1. In addition to the Bcl-2 homology (BH) domains 1 and 2 and the transmembrane sequence, Bok also has a BH3 domain believed to be important for dimerization with selective anti-apoptotic Bcl-2 proteins and cell killing. Bok interacts strongly with some (Mcl-1, BHRF1, and Bfl-1) but not other (Bcl-2, Bcl-xL, and Bcl-w) anti-apoptotic members. In addition, cell killing induced by Bok was suppressed following coexpression with Mcl-1 and BHRF1, but not with Bcl-2, further indicating that Bok heterodimerized only with selective anti-apoptotic Bcl-2 proteins. Bok was highly expressed in the ovary, testis and uterus.Synonyms: Bcl-2-like protein 9, Bcl-2-related ovarian killer protein, Bcl2-L-9, Hbok
- ID gène
- 29884
- NCBI Accession
- NP_059008
- UniProt
- Q792S6
- Pathways
- Positive Regulation of Endopeptidase Activity
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