Cathepsin L anticorps

N° du produit ABIN127049

Détail du produit anti-Cathepsin L anticorps

Antigène: Cathepsin L (CTSL1) (Cathepsin L1 (CTSL1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cathepsin L est non-conjugé

Application: Western Blotting (WB)

Specificité: Detects both the proenzyme and the mature form of cathepsin L.

Purification: Affinity purified

Immunogène: Synthetic peptide surrounding amino acid 223 of human Cathepsin L

Information d'application

Indications d'application: Western Blot: 0.5-4 μg/mL, Jurkat cell lysate can be used as a positive control.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.2 mg/mL

Buffer: PBS, pH 7.2, containing 50 % glycerol, 1 % BSA, 0.02 % thimerosal.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C/-80 °C

Stockage commentaire: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -20 °C to -70 °C.

Détails sur Cathepsin L

Antigène: Cathepsin L (CTSL1) (Cathepsin L1 (CTSL1))

Autre désignation: Cathepsin L1 (CTSL1 Produits)

Synonymes: anticorps CATL, anticorps CTSL1, anticorps MEP, anticorps 1190035F06Rik, anticorps Ctsl1, anticorps fs, anticorps nkt, anticorps CATHL, anticorps CatL, anticorps Ctsl, anticorps CTSL, anticorps mep, anticorps catl, anticorps ctsl, anticorps cpl-1, anticorps MGC80629, anticorps MGC107932, anticorps LOC663234, anticorps 26-29-p, anticorps Cp1, anticorps si:dkey-121a11.6, anticorps CTSV, anticorps catL, anticorps cb15, anticorps ctsl1b, anticorps hgg1, anticorps wu:fb30g09, anticorps zgc:92089, anticorps cathepsin L, anticorps cathepsin V, anticorps cathepsin L L homeolog, anticorps cathepsin L1, anticorps Cathepsin L1, anticorps Cathepsin L, anticorps testin gene, anticorps cathepsin 12, anticorps cathepsin Lb, anticorps cathepsin L.1, anticorps CTSL, anticorps Ctsl, anticorps CTSV, anticorps ctsl.L, anticorps ctsl, anticorps LOC100008830, anticorps catl1, anticorps 26-29-p, anticorps catl, anticorps Tsp_11596, anticorps Testin, anticorps cts12, anticorps LOC102156614, anticorps ctslb, anticorps ctsl.1

Sujet: Cathepsin L is a normal lysosomal cysteine endoproteases that is expressed in all cells. The latent 39 kDa pro-Cathepsin L must be processed by cleavage of the 96 amino acid propeptide, to generate the active two-chain form made up of 21 and 5 kDa subunits. Mature Cathepsin L is normally localized in the lysosomes where it plays a major role in intracellular protein catabolism. The fact that Cathepsin L is also capable of degrading extracellular matrix proteins suggests that it may play a role in invation and metastasis and could be a useful prognostic indicator for cancer.Synonyms: CTSL, CTSL1, Cathepsin-L1, MEP, Major excreted protein

ID gène: 1514

NCBI Accession: NP_001903

UniProt: P07711

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades