SMAD5 anticorps

N° du produit ABIN127143

Détail du produit anti-SMAD5 anticorps

Antigène: SMAD5 (SMAD, Mothers Against DPP Homolog 5 (SMAD5))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SMAD5 est non-conjugé

Application: Western Blotting (WB)

Specificité: The antibody recognizes ~60 kDa Smad5.

Purification: Affinity Purified

Information d'application

Indications d'application: Western Blot: 1-4 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS containing 50 % glycerol, 1 % BSA, and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C/-80 °C

Stockage commentaire: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.

Détails sur SMAD5

Antigène: SMAD5 (SMAD, Mothers Against DPP Homolog 5 (SMAD5))

Autre désignation: SMAD5 (SMAD5 Produits)

Synonymes: anticorps DWFC, anticorps JV5-1, anticorps MADH5, anticorps Madh5, anticorps SBN, anticorps fb67b04, anticorps mad, anticorps madh5, anticorps sb:cb400, anticorps smd5, anticorps wu:fb67b04, anticorps SMAD5, anticorps DKFZp468M0619, anticorps 1110051M15Rik, anticorps AI451355, anticorps Dwf-C, anticorps MusMLP, anticorps SMAD family member 5, anticorps SMAD5, anticorps Smad5, anticorps smad5

Sujet: Smad proteins, the mammalian homologs of the Drosophila Mothers against dpp (Mad), have been implicated as downstream effectors of TGFβ/BMP signaling. Smad1, Smad5, and Smad8 are effectors of BMP2 and BMP4 function while Smad2 and Smad3 are involved in TGF-β and activin-mediated growth modulation. Smad4 has been shown to mediate all of the above activities through interaction with various Smad family members. Smad6 and Smad7 regulate the response to activin/TGFβ signaling by interfering with TGFβ-mediated phosphorylation of other Smad family members.Synonyms: JV5-1, MAD homolog 5, MADH5, Mothers against DPP homolog 5, Mothers against decapentaplegic homolog 5, SMAD 5, SMAD family member 5, SMAD-5

ID gène: 4090

NCBI Accession: NP_001001419

UniProt: Q99717