SMAD5 anticorps
Aperçu rapide pour SMAD5 anticorps (ABIN127143)
Antigène
Voir toutes SMAD5 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Specificité
- The antibody recognizes ~60 kDa Smad5.
-
Purification
- Affinity Purified
-
-
-
-
Indications d'application
-
Western Blot: 1-4 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
-
-
-
Concentration
- 0.5 mg/mL
-
Buffer
- PBS containing 50 % glycerol, 1 % BSA, and 0.02 % sodium azide.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Avoid repeated freezing and thawing.
-
Stock
- -20 °C/-80 °C
-
Stockage commentaire
- Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
-
-
- SMAD5 (SMAD, Mothers Against DPP Homolog 5 (SMAD5))
-
Autre désignation
- SMAD5
-
Sujet
- Smad proteins, the mammalian homologs of the Drosophila Mothers against dpp (Mad), have been implicated as downstream effectors of TGFβ/BMP signaling. Smad1, Smad5, and Smad8 are effectors of BMP2 and BMP4 function while Smad2 and Smad3 are involved in TGF-β and activin-mediated growth modulation. Smad4 has been shown to mediate all of the above activities through interaction with various Smad family members. Smad6 and Smad7 regulate the response to activin/TGFβ signaling by interfering with TGFβ-mediated phosphorylation of other Smad family members.Synonyms: JV5-1, MAD homolog 5, MADH5, Mothers against DPP homolog 5, Mothers against decapentaplegic homolog 5, SMAD 5, SMAD family member 5, SMAD-5
-
ID gène
- 4090
-
NCBI Accession
- NP_001001419
-
UniProt
- Q99717
Antigène
-