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MMP13 anticorps

Cet anticorps anti-MMP13 est un anticorps Lapin Polyclonal détectant MMP13 dans WB, IP et IHC (p). Adapté pour Humain, Souris, Rat, Lapin, Boeuf (Vache) et Cheval.
N° du produit ABIN127179

Aperçu rapide pour MMP13 anticorps (ABIN127179)

Antigène

Voir toutes MMP13 Anticorps
MMP13 (Matrix Metallopeptidase 13 (Collagenase 3) (MMP13))

Reactivité

  • 118
  • 52
  • 36
  • 17
  • 17
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Humain, Souris, Rat, Lapin, Boeuf (Vache), Cheval

Hôte

  • 129
  • 19
  • 11
Lapin

Clonalité

  • 133
  • 26
Polyclonal

Conjugué

  • 74
  • 22
  • 13
  • 7
  • 6
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
Cet anticorp MMP13 est non-conjugé

Application

  • 129
  • 71
  • 44
  • 31
  • 27
  • 27
  • 26
  • 24
  • 17
  • 8
  • 8
  • 3
  • 3
  • 1
  • 1
Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Specificité

    The antibody recognizes the proenzyme (~60 kDa) and the cleaved fragments (34 kDa and 48 kDa) of MMP-13.

    Réactivité croisée (Details)

    Species reactivity (expected):Mouse, Rat, Equine (Horse), Rabbit and Bovine.
    Species reactivity (tested):Human.

    Purification

    Affinity Chromatography.

    Immunogène

    Synthetic peptide surrounding amino acid 454 of Rat MMP-13.
  • Indications d'application

    Western blotting (0.5-4 μg/mL) . Immunoprecipitation. Immunohistochemistry (works with Paraffin Embedded Sections).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Concentration

    0.5 mg/mL

    Buffer

    PBS containing 30 % Glycerol, 0.5 % BSA and 0.01 % Thimerosal.

    Agent conservateur

    Thimerosal (Merthiolate)

    Précaution d'utilisation

    This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freezing and thawing.

    Stock

    -20 °C/-80 °C

    Stockage commentaire

    Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
  • Antigène

    MMP13 (Matrix Metallopeptidase 13 (Collagenase 3) (MMP13))

    Autre désignation

    MMP-13

    Sujet

    The Matrix Metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-13 (also designated collagenase-3) is produced by breast carcinomas and degrades collagen type I, II, III.Synonyms: Collagenase 3, MMP13, Matrix metalloproteinase-13

    ID gène

    4322

    NCBI Accession

    NP_002418

    UniProt

    P45452
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