LIMK2 anticorps (C-Term)

N° du produit ABIN127209

Cet anticorps anti-LIMK2 Polyclonal Lapin (ABIN127209) détecte spécifiquement LIMK2 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour LIMK2 anticorps (C-Term) (ABIN127209)

Antigène: LIMK2 (LIM Domain Kinase 2 (LIMK2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LIMK2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-LIMK2 anticorps

Épitope: C-Term

Specificité: The antibody detects 70 kDa LIMK2 protein. It does not cross-react with LIMK1. The antibody recognizes ~35 kDa PHAP III.

Purification: Affinity Purified

Immunogène: Synthetic peptide corresponding to the C-terminus of human LIMK2.

Information d'application

Indications d'application: Western Blot: 1-4 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS, pH 7.2, containing 50 % glycerol, 1 % BSA, 0.02 % thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C/-80 °C

Stockage commentaire: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.

Détails sur LIMK2

Antigène: LIMK2 (LIM Domain Kinase 2 (LIMK2))

Autre désignation: LIMK2

Sujet: LIM kinases (LIMK1 and LIMK2) are serine/threnine kinases that have two zinc finger motifs, known as LIM motifs in their N-terminal regulatory domain. LIM kinases are involved in actin cytoskeleton regulation through Rho-family GTPases and downstream kinases PAKs and ROCK. PAK1 and ROCK phosphorylate LIMK1 and LIMK2, which increases the activity of the kinases. Activated LIM kinases inhibit the actin depolymerization activity of cofilin by phosphorylation at the N-terminus of Cofilin.Synonyms: EC=2.7.11.1, LIM domain kinase 2, LIMK-2, LIMK2

ID gène: 3985

NCBI Accession: NP_005560

UniProt: P53671