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HDAC6 anticorps (N-Term)
HDAC6
Reactivité: Humain, Souris, Rat
WB, IHC (p)
Hôte: Lapin
Polyclonal
unconjugated
Détail du produit anti-HDAC6 anticorps
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Antigène
Voir toutes HDAC6 Anticorps
HDAC6
(Histone Deacetylase 6 (HDAC6))
Épitope
Tous les épitopes à travers HDAC6 Anticorps.
N-Term
Reactivité
Toutes les réactivités sur HDAC6 Anticorps
Humain, Souris, Rat
Hôte
Toutes les hôtes sur HDAC6 Anticorps
Lapin
Clonalité
Toutes les clonalités sur HDAC6 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers HDAC6 Anticorps
Cet anticorp HDAC6 est non-conjugé
Application
Tous les applications à travers HDAC6 Anticorps.
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Specificité
The antibody detects ~134 kDa HDAC-6. This antibody does not cross-react with other HDAC proteins including HDAC1, 2, 3, 4, 5, 7, and 8.
Purification
Affinity Chromatography.
Immunogène
Synthetic peptide mapping to the N-terminus of mouse HDAC-6.
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Information d'application
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Indications d'application
Western Blot: 0.5-4 μg/mL. Immunohistochemistry: 20 μg/mL. Positive Control: Mouse small intestine tissue lysate. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Stockage
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Concentration
0.2 mg/mL
Buffer
PBS, pH 7.2, containing 30 % Glycerol, 0.5 % BSA and 0.01 % thimerosal.
Agent conservateur
Thimerosal (Merthiolate)
Précaution d'utilisation
This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
-20 °C/-80 °C
Stockage commentaire
Store the antibody undiluted at -20 °C or (in aliquots) at -70 °C for longer.
Détails sur HDAC6
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Antigène
HDAC6
(Histone Deacetylase 6 (HDAC6))
Autre désignation
HDAC6 (HDAC6 Produits )
Synonymes
anticorps HD6, anticorps Hd6, anticorps Hdac5, anticorps Sfc6, anticorps mHDA2, anticorps CG6170, anticorps DHDAC2, anticorps DmHDAC2, anticorps Dmel\\CG6170, anticorps HDAC, anticorps HDAC2, anticorps dHDAC2, anticorps dHDAC6, anticorps dmHDA404, anticorps hdac6, anticorps MGC53140, anticorps wu:fc31d02, anticorps dsim_GLEANR_17355, anticorps DsimGD17207, anticorps GD17207, anticorps HDAC6, anticorps ATHDA6, anticorps AXE1, anticorps HISTONE DEACETYLASE 6, anticorps MDC12.7, anticorps MDC12_7, anticorps RNA-MEDIATED TRANSCRIPTIONAL SILENCING 1, anticorps RPD3B, anticorps RTS1, anticorps SIL1, anticorps histone deacetylase 6, anticorps histone deacetylase 6, anticorps Histone deacetylase 6, anticorps histone deacetylase 6 L homeolog, anticorps GD17207 gene product from transcript GD17207-RB, anticorps Histone DeAcetylase, anticorps HDAC6, anticorps Hdac6, anticorps hdac6.L, anticorps hdac6, anticorps Dsim\HDAC6, anticorps PTRG_03035, anticorps HDA6, anticorps hda-6
Sujet
Human HDAC6 (1215 a.a. residues) possesses two separate putative catalytic domains, both of which are fully functional and contribute independently to the overall activity of HDAC6. A very potent NES is present at the amino-terminus of HDAC6, which was found to play an important role in regulating the shuttling of HDAC6 protein between cytoplasm and nucleus. The shuttling process may be a critical regulatory mechanism of HDAC6 function. HDAC6 may participate in coordinating expression of a group of genes involved in the remoldeling of chromatin during cell differentiation.Synonyms: HD6, Histone deacetylase 6, JM21, KIAA0901
ID gène
10013
NCBI Accession
NP_006035
UniProt
Q9UBN7
Pathways
Intracellular Steroid Hormone Receptor Signaling Pathway , Regulation of Intracellular Steroid Hormone Receptor Signaling
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