HDAC7 anticorps

N° du produit ABIN127244

L’anticorps anti-HDAC7 Polyclonal Lapin est utilisé pour la détection de HDAC7 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, IHC (p) et IP.

Aperçu rapide pour HDAC7 anticorps (ABIN127244)

Antigène: HDAC7 (Histone Deacetylase 7 (HDAC7))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HDAC7 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)

Détail du produit anti-HDAC7 anticorps

Specificité: The antibody detects ~105 kDa HDAC7.

Purification: Affinity Purified

Immunogène: Synthetic peptide surrounding amino acid 921 of murine HDAC7

Information d'application

Indications d'application: Western blotting (0.5-4 μg/mL). Mouse small intestine tissue lysate can be use as apositive control. Based on researchers feedback, this antibody can also be used inimmunoprecipitation (20-40 μg/mL) and immunohistochemistry (20-40 μg/mL).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.2 mg/mL

Buffer: PBS, pH 7.2, containing 30 % glycerol, 0.5 % BSA, 0.01 % thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C/-80 °C

Stockage commentaire: Store (in aliquots) at -20 °C to -70 °C.

Détails sur HDAC7

Antigène: HDAC7 (Histone Deacetylase 7 (HDAC7))

Autre désignation: HDAC7

Sujet: Human HDAC7 is composed of 912 amino acid residues. Although HDAC7 is localized mostly to the cell nucleus, it is also found in the cytoplasm, suggesting nucleo-cytoplasmic shuttling. The histone deacetylase activity of HDAC7 maps to a carboxy-terminal domain and is dependent on interaction with class I HDACs in the nucleus. HDAC7 catalyzes removal of acetyl-groups from acetyl-lysines of histones and promotes compaction of chromatin in these regions, leading to the inhibition of gene transcription.Synonyms: HD7, HD7a, HDAC7A, Histone deacetylase 7

ID gène: 51564

NCBI Accession: NP_001091886

UniProt: Q8WUI4

Pathways: Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development