UBA1 anticorps

N° du produit ABIN129529

Détail du produit anti-UBA1 anticorps

Antigène: UBA1 (Ubiquitin-Like Modifier Activating Enzyme 1 (UBA1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UBA1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Attributs du produit: Concentration Definition: by UV absorbance at 280 nm

Immunogène: Anti-Ubiquitin Activating Enzyme E1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a recombinant protein corresponding to full length Human Ubiquitin Activating Enzyme E1.
Immunogentype:Recombinant

Isotype: IgG

Information d'application

Indications d'application: This purified antibody has been tested for use in ELISA, immunohistochemistry and western blot.  Specific conditions for reactivity should be optimized by the end user.  Expect a band at ~118 kDa in size corresponding to UBE1 by western blotting in the appropriate cell lysate or extract.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Restore with deionized water (or equivalent)

Concentration: 5.0 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Détails sur UBA1

Antigène: UBA1 (Ubiquitin-Like Modifier Activating Enzyme 1 (UBA1))

Autre désignation: Ubiquitin Activating Enzyme E1 (UBA1 Produits)

Synonymes: anticorps A1S9, anticorps A1S9T, anticorps A1ST, anticorps AMCX1, anticorps GXP1, anticorps POC20, anticorps SMAX2, anticorps UBA1A, anticorps UBE1, anticorps UBE1X, anticorps DDBDRAFT_0190927, anticorps DDBDRAFT_0220497, anticorps DDB_0190927, anticorps DDB_0220497, anticorps Sbx, anticorps Ube-1, anticorps Ube1x, anticorps a1s9, anticorps a1s9t, anticorps a1st, anticorps amcx1, anticorps gxp1, anticorps poc20, anticorps smax2, anticorps uba1a, anticorps ube1, anticorps ube1x, anticorps uba1, anticorps uba1b, anticorps ube, anticorps zgc:66143, anticorps wu:fa01e08, anticorps wu:fb30f01, anticorps wu:fi21c11, anticorps wu:fj14g11, anticorps ubiquitin like modifier activating enzyme 1, anticorps ubiquitin activating enzyme E1, anticorps Ubiquitin-conjugating enzyme E1, anticorps ubiquitin-like modifier activating enzyme 1, anticorps ubiquitin-like modifier activating enzyme 1 S homeolog, anticorps ubiquitin-like modifier activating enzyme 1 L homeolog, anticorps UBA1, anticorps uae1, anticorps GL50803_4083, anticorps GL50803_10661, anticorps Uba1, anticorps uba1.S, anticorps uba1.L, anticorps uba1, anticorps ptr3

Sujet: Ubiquitin Activating Enzyme (E1), also known as A1S9 and UBE1, is responsible for the first step in ubiquitin-protein isopeptide bond formation.  E1 catalyzes the activation of the C-terminal carboxyl group of ubiquitin by forming a high-energy thioester bond in an ATP-dependent manner. UBE1 is monomeric and contains two active sites within the E1 molecule, allowing it to bind two ubiquitin moieties at a time, with a new ubiquitin forming an adenylate intermediate as the previous one is transferred to the thiol site.  Alternative splicing results in 2 transcript variants encoding the same protein, but with different 5' UTR. Isoform 1 has a different 5' noncoding exon compared to isoform 2.  Both variants encode the same protein.
Synonyms: A1S9 antibody, A1S9 protein antibody, A1S9T and BN75 temperature sensitivity complementing antibody, A1S9T antibody, A1ST antibody, GXP 1 antibody

ID gène: 7317, 23510338

UniProt: P22314