NCS1 anticorps

N° du produit ABIN129571

N° du produit (Fournisseur): 600-401-216

Cet anticorps Lapin Polyclonal détecte spécifiquement NCS1 dans WB, ELISA, IF, MA et FM. Il présente une réactivité envers Souris.

Aperçu rapide pour NCS1 anticorps (ABIN129571)

Antigène: NCS1 (Neuronal Calcium Sensor 1 (NCS1))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NCS1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Multiplex Assay (MA), Fluorescence Microscopy (FM)

Détail du produit anti-NCS1 anticorps

N° du produit (Fournisseur): 600-401-216

Fournisseur: Rockland

Fonction: Frequenin Antibody

Réactivité croisée (Details): Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Rabbit Serum.

Attributs du produit: Synonyms: rabbit anti-FREQUENIN antibody, NCS-1, FLUP, FREQ, Neuronal calcium sensor 1, frequenin homolog antibody, Frequenin-like protein antibody, NCS 1 antibody, NCS1 antibody

Purification: This product was prepared from monospecific antiserum by immunoaffinity chromatography using Frequenin (recombinant) coupled to agarose beads.

Stérilité: Sterile filtered

Immunogène:

Immunogen: Frequenin (recombinant from Mouse with extensive post-translational modifications)

Immunogen Type: Recombinant Protein

Isotype: IgG

Information d'application

Indications d'application:

Application Note: This product was assayed by immunoblot and found to be reactive against Frequenin at a dilution of 1:5000 followed by reaction with Peroxidase conjugated Affinity Purified anti-Rabbit IgG [H&L] (Goat) code #611-1302.  Anti-Frequenin is suitable for the detection by immunoblot of human, mouse and rat Frequenin. Anti-Frequenin has also been tested for use in IF using Hippocampal neurons of 17 day old NMRI mice.

Western Blot Dilution: 1:500- 1:2,000

ELISA Dilution: 1:10,000 - 1:50,000

IF Microscopy Dilution: 1:100-1:2500

Other: User Optimized

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 2.0 mg/mL

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: None

Preservative: 0.01 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Date de péremption: 12 months

Détails sur NCS1

Antigène: NCS1 (Neuronal Calcium Sensor 1 (NCS1))

Autre désignation: Ncs1

Sujet: Background: Frequenin, or Neuronal calcium sensor, is a regulator of G protein-coupled receptor phosphorylation in a calcium dependent manner. It directly regulates GRK1 (RHOK), but not GRK2 to GRK5. It can substitute for calmodulin and it stimulates PI4KB kinase activity. It is involved in long-term synaptic plasticity through its interaction with PICK1. Ncs1 may also play a role in neuron differentiation through inhibition of the activity of N-type voltage-gated calcium channel.

ID gène: 14299

NCBI Accession: NP_062655

UniProt: Q8BNY6