ANKRD32 anticorps (AA 75-100)
Aperçu rapide pour ANKRD32 anticorps (AA 75-100) (ABIN129614)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 75-100
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N° du produit (Fournisseur)
- 600-401-681
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Fournisseur
- Rockland
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Fonction
- HALLEN Antibody
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Attributs du produit
- Synonyms: rabbit anti-HALLEN antibody, Ankyrin repeat domain-containing protein 32, ANKRD32, cDNA FLJ57532, BRCT domain-containing protein 1, BRCTD1 antibody, Smc5/6 localization factor 1, SLF1, SMC5-SMC6 Complex Localization Factor 1
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Purification
- This is an affinity purified antibody produced by immunoaffinity chromatography using the immunizing peptide after immobilization to a solid phase.
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Stérilité
- Sterile filtered
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Immunogène
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Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region near amino acids 75-100 of Human Hallen. Hallen is a novel BRCT domain containing protein.
Immunogen Type: Conjugated Peptide
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Isotype
- IgG
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Indications d'application
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Application Note: This affinity purified antibody has been tested for use in ELISA against the immunizing peptide. Reactivity in other immunoassays is unknown.
Western Blot Dilution: 1:500- 1:2,000
ELISA Dilution: 1:10,000 - 1:50,000
Other: User Optimized
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1.33 mg/mL
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Buffer
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide -
Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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Date de péremption
- 12 months
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- ANKRD32 (Ankyrin Repeat Domain 32 (ANKRD32))
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Autre désignation
- SLF1
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Sujet
- Background: Anti-HALLEN plays a role in the DNA damage response pathway by regulating post replication repair of UV-damaged DNA and genomic stability maintenance. The SLF1-SLF2 complex acts to link RAD18 with the SMC5-SMC6 complex at replication-coupled interstrand cross-links and DNA double-strand breaks sites on chromatin during DNA repair in response to stalled replication forks. Anti-HALLEN promotes the recruitment of SLF2 and the SMC5-SMC6 complex to DNA lesions. Anti-Hallen Antibody is useful for researchers interested in DNA damage and repair.
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ID gène
- 84250
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NCBI Accession
- NP_115666
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UniProt
- Q9BQI6
Antigène
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