RIF1 anticorps (AA 2375-2419)

N° du produit ABIN129646

N° du produit (Fournisseur): 600-401-871

Cet anticorps Lapin Polyclonal détecte spécifiquement RIF1 dans WB et ELISA. Il présente une réactivité envers Souris et a été mentionné dans 1 publication.

Aperçu rapide pour RIF1 anticorps (AA 2375-2419) (ABIN129646)

Antigène: RIF1 (RAP1 Interacting Factor Homolog (RIF1))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RIF1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-RIF1 anticorps

Épitope: AA 2375-2419

N° du produit (Fournisseur): 600-401-871

Fournisseur: Rockland

Fonction: Rif1 Antibody

Réactivité croisée (Details): This affinity purified antibody is directed against mouse Rif1 protein.

Attributs du produit: Synonyms: rabbit anti-Rif1 antibody, Rif-1, Rif 1, Telomere-associated protein RIF1, Rap1 interacting factor 1 antibody, Rap1 interacting factor 1 homolog antibody, mRif1, Rap-1

Purification: The product was affinity purified from monospecific antiserum by immunoaffinity purification.

Stérilité: Sterile filtered

Immunogène:

Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to C-Terminal region near amino acids 2375-2419 of Mouse Rif1.

Immunogen Type: Conjugated Peptide

Isotype: IgG

Information d'application

Indications d'application:

Application Note: This affinity purified antibody has been tested for use in ELISA and by western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 265 kDa in size corresponding to Rif1 by western blotting in the appropriate cell lysate or extract.

Western Blot Dilution: 1:500 - 1:3,000

ELISA Dilution: 1:5,000 - 1:40,000

Other: User Optimized

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.6 mg/mL

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: None

Preservative: 0.01 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Date de péremption: 12 months

Références pour anticorps anti-RIF1 (ABIN129646)

Tanaka, Muto, Shima, Katoh, Sax, Tajima, Brydun, Ikura, Yoshizawa, Masai, Hoshikawa, Noda, Nio, Ochiai, Igarashi: "Epigenetic Regulation of the Blimp-1 Gene (Prdm1) in B Cells Involves Bach2 and Histone Deacetylase 3." dans: The Journal of biological chemistry, Vol. 291, Issue 12, pp. 6316-30, (2016) (PubMed).

Détails sur RIF1

Antigène: RIF1 (RAP1 Interacting Factor Homolog (RIF1))

Autre désignation: Rif1

Sujet: Background: Rif1 (also known as telomere-associated protein RIF1 and Rap1-interacting factor 1) is a mouse ortholog of the yeast Rif1 family of telomere-associated proteins identified on the basis of its high expression in primordial germ cells and embryo-derived pluripotent stem cell lines.  Mouse Rif1 is a protein involved in negative regulation of telomere length.  It is also localized to ATM dependent DNA damage foci and may act at the chromatin level to allow access to some factors.

ID gène: 51869, 68565756

UniProt: Q6PR54

Pathways: Stem Cell Maintenance