LY9 anticorps
Aperçu rapide pour LY9 anticorps (ABIN1302441)
Antigène
Voir toutes LY9 (CD229) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Anti-Hu CD229 Purified
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Specificité
- The mouse monoclonal antibody HLy9.25 (also known as HLy9.1.25) recognizes an extracellular epitope of CD229 / Ly9, a 100-120 kDa cell surface glycoprotein expressed on T and B cells.
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Réactivité croisée (Details)
- Human
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Purification
- Purified by protein-A affinity chromatography.
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Pureté
- > 95 % (by SDS-PAGE)
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Immunogène
- CD299-transfected 300.19 pre-B cell line
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Isotype
- IgG1
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Indications d'application
- Flow cytometry: Recommended dilution: 6 μg/mL, positive control: peripheral blood lymphocytes.
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Restrictions
- For Research Use only
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Concentration
- 1 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Do not freeze.
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Stock
- 4 °C
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Stockage commentaire
- Store at 2-8°C. Do not freeze.
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- LY9 (CD229) (Lymphocyte Antigen 9 (CD229))
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Autre désignation
- CD229
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Sujet
- Lymphocyte antigen 9,CD229 (Ly9) is a cell surface receptor of the CD150 family, which includes also e.g. CD48 and CD224. Receptors of this family regulate cytokine production and cytotoxicity of lymphocytes and NK cells. High levels of CD229 are found on T and B cells, where its expression increases during their maturation. It is absent on granulocytes, bone marrow-derived dendritic cells, platelets and erythrocytes. CD229 has been also reported on mouse monocytes and NK cells. CD229 interacts homophilically through its N-terminal domain and localizes to the contact site between T cells and antigen presenting B cells during antigen-dependent immune synapse formation.,SLAMF3, LY9
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ID gène
- 4063
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UniProt
- Q9HBG7
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Pathways
- BCR Signaling
Antigène
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