CoREST anticorps (AA 109-293)

N° du produit ABIN1304609

L’anticorps Souris Monoclonal anti-CoREST a été validé pour WB, IHC, ICC et IP. Il convient pour détecter CoREST dans des échantillons de Humain.

Aperçu rapide pour CoREST anticorps (AA 109-293) (ABIN1304609)

Antigène: CoREST (RCOR1) (REST Corepressor 1 (RCOR1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CoREST est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Clone: K72-8

Détail du produit anti-CoREST anticorps

Épitope: AA 109-293

Specificité: No off-targets reported

Réactivité croisée: Humain, Souris, Rat

Attributs du produit:

Description: Our Anti-Co-Rest/RCOR1 mouse monoclonal primary antibody is produced in-house from hybridoma clone K72/8. It detects human, mouse, and rat Co-Rest/RCOR1, and is purified by Protein A chromatography. It is great for use in IHC, ICC, IP, WB.

Manufacturer Comment: We produce our Co-Rest/RCOR1 mouse monoclonal primary antibody from hybridoma clone K72/8. It is great in IHC, ICC, IP, WB and is purified by Protein A chromatography.

Purification: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography.

Pureté: > 90% specific antibody

Immunogène: Fusion protein amino acids 109-293 of human Co-Rest (accession number Q9UKL0), includes ELM2 and SANT domains, produced recombinantly in E. Coli

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 10 mM Tris, 50 mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

Stock: 4 °C,-20 °C

Stockage commentaire: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Date de péremption: 24 months

Détails sur CoREST

Antigène: CoREST (RCOR1) (REST Corepressor 1 (RCOR1))

Autre désignation: RCOR1

Sujet:

Synonyms: REST corepressor 1 (Protein CoREST)

Target Description: REST Corepressor 1, CoREST or RCOR is encoded by the gene RCOR1 and is a member of the CoREST family of proteins. CoREST is a corepressor to the RE1 silencing transcription factor/neural restrictive silencing (REST) transcription factor and is part of a multiprotein complex (BHC complex) that represses transcription of neuron-specific genes in non-neuronal cells. This complex determines neural cell differentiation. CoREST is ubiquitously expressed in the nucleus of cells. Diseases associated with this gene include Huntington Disease and Loeys-Dietz Syndrome 1.

Gene Name Alternatives: RCOR1 KIAA0071 RCOR

Poids moléculaire: 66-80 kDa (depending on gel system used)

NCBI Accession: NP_055971

Pathways: Regulation of Hormone Metabolic Process, Chromatin Binding