MESDC2 anticorps (AA 30-95)

N° du produit ABIN1304817

Cet anticorps anti-MESDC2 est un anticorps Souris Monoclonal détectant MESDC2 dans WB, IHC, ICC et IP. Adapté pour Souris.

Aperçu rapide pour MESDC2 anticorps (AA 30-95) (ABIN1304817)

Antigène: MESDC2 (Mesoderm Development Candidate 2 (MESDC2))

Reactivité: Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MESDC2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Clone: N88-12

Détail du produit anti-MESDC2 anticorps

Épitope: AA 30-95

Specificité: No off-targets reported

Réactivité croisée: Humain, Souris, Rat

Attributs du produit:

Description: Our Anti-MESD mouse monoclonal primary antibody is produced in-house from hybridoma clone N88/12. It detects human, mouse, and rat MESD, and is purified by Protein A chromatography. It is great for use in IHC, ICC, IP, WB.

Manufacturer Comment: We produce our MESD mouse monoclonal primary antibody from hybridoma clone N88/12. It is great in IHC, ICC, IP, WB and is purified by Protein A chromatography.

Purification: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography.

Pureté: > 90% specific antibody

Immunogène: Fusion protein amino acids 30-95 and 118-180 (lacking VSD domain) of mouse MESD (accession number Q9ERE7) produced recombinantly in E. Coli

Isotype: IgG2b

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 10 mM Tris, 50 mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

Stock: 4 °C,-20 °C

Stockage commentaire: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Date de péremption: 24 months

Détails sur MESDC2

Antigène: MESDC2 (Mesoderm Development Candidate 2 (MESDC2))

Autre désignation: MESD

Sujet:

Synonyms: LRP chaperone MESD (LDLR chaperone MESD) (Mesoderm development candidate 2) (Mesoderm development protein)

Target Description: Mesoderm Development LRP Chaperone is encoded by the gene MESD. MESD is a member of the MESD family. MESD is a chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). MESD acts as a modulator of the Wnt pathway through chaperoning the coreceptors of the canonical Wnt pathway, LRP5 and LRP6, to the plasma membrane. MESD is essential for the specification of embryonic polarity and mesoderm induction. MESD plays an essential role neuromuscular junction (NMJ) formation by promoting cell-surface expression of LRP4. MESD is expressed in many tissues, but not in skeletal muscles. Diseases associated with MESD include Osteogenesis Imperfecta, Type Xx and Epilepsy, Nocturnal Frontal Lobe, 2.

Gene Name Alternatives: Mesd Mesdc2

Poids moléculaire: 26 kDa

UniProt: Q9ERE7