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KCNT1 anticorps (AA 1168-1237)

Cet anticorps Souris Monoclonal détecte spécifiquement KCNT1 dans WB, IHC et ICC. Il présente une réactivité envers Rat.
N° du produit ABIN1304962

Aperçu rapide pour KCNT1 anticorps (AA 1168-1237) (ABIN1304962)

Antigène

Voir toutes KCNT1 Anticorps
KCNT1 (Potassium Channel, Subfamily T, Member 1 (KCNT1))

Reactivité

  • 35
  • 23
  • 6
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Rat

Hôte

  • 35
  • 16
Souris

Clonalité

  • 35
  • 16
Monoclonal

Conjugué

  • 13
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp KCNT1 est non-conjugé

Application

  • 33
  • 22
  • 15
  • 13
  • 13
  • 12
  • 11
  • 10
  • 4
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Clone

N3-26
  • Épitope

    • 15
    • 15
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1168-1237

    Specificité

    No off-targets reported

     Réactivité croisée

    Humain, Marine Mollusks (Liolophura), Souris, Rat

    Attributs du produit

    Description: Our Anti-Slo2.2/Slack K+ channel mouse monoclonal primary antibody is produced in-house from hybridoma clone N3/26. It is KO validated, detects human, marine mollusk, mouse, and rat Slo2.2/Slack K+ channel, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.

    Manufacturer Comment: We produce our Slo2.2/Slack K+ channel mouse monoclonal primary antibody from hybridoma clone N3/26. It is great in IHC, ICC, WB and is purified by Protein A chromatography.

    Purification

    Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography.

    Pureté

    > 90% specific antibody

    Immunogène

    Fusion protein amino acids 1168-1237 of rat Slo2.2 (accession number NP_068625) produced recombinantly in E. Coli

    Isotype

    IgG1
  • Indications d'application

    Dilution Range: IHC: 1:400

    Dilution Range: ICC: 1:250

    Dilution Range: WB: 1:1000

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    10 mM Tris, 50 mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

    Date de péremption

    24 months
  • Antigène

    KCNT1 (Potassium Channel, Subfamily T, Member 1 (KCNT1))

    Autre désignation

    Slo2.2

    Sujet

    Synonyms: Potassium channel subfamily T member 1 (Sequence like a calcium-activated potassium channel subunit)

    Target Description: Potassium channel subfamily T member 1 or -KCNT1/Slo2.2/Slack K+ channel is encoded by the gene KCNT1. Slo2.2 is a member of the the voltage-gated ion channel (vic) superfamily, and the KCNT protein family, which is made of KCNT1 and KCNT2. Slo2.2 functions as an outwardly rectifying potassium channel subunit to contribute to ion conductance and signaling pathways. Slo2.2 can be activated by high intracellular sodium or chloride levels. Slo2.2 is expressed at the membrane in many areas of the brain, brainstem, spinal cord, spleen and liver. Mutations in this gene cause the early-onset epileptic disorders

    Gene Name Alternatives: Kcnt1 Slack

    Poids moléculaire

    140 kDa

    NCBI Accession

    NP_068625
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