KCNT1 anticorps (AA 1168-1237)
Aperçu rapide pour KCNT1 anticorps (AA 1168-1237) (ABIN1304962)
Antigène
Voir toutes KCNT1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 1168-1237
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Specificité
- No off-targets reported
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Réactivité croisée
- Humain, Marine Mollusks (Liolophura), Souris, Rat
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Attributs du produit
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Description: Our Anti-Slo2.2/Slack K+ channel mouse monoclonal primary antibody is produced in-house from hybridoma clone N3/26. It is KO validated, detects human, marine mollusk, mouse, and rat Slo2.2/Slack K+ channel, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.
Manufacturer Comment: We produce our Slo2.2/Slack K+ channel mouse monoclonal primary antibody from hybridoma clone N3/26. It is great in IHC, ICC, WB and is purified by Protein A chromatography.
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Purification
- Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography.
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Pureté
- > 90% specific antibody
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Immunogène
- Fusion protein amino acids 1168-1237 of rat Slo2.2 (accession number NP_068625) produced recombinantly in E. Coli
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Isotype
- IgG1
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Indications d'application
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Dilution Range: IHC: 1:400
Dilution Range: ICC: 1:250
Dilution Range: WB: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 10 mM Tris, 50 mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
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Date de péremption
- 24 months
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- KCNT1 (Potassium Channel, Subfamily T, Member 1 (KCNT1))
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Autre désignation
- Slo2.2
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Sujet
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Synonyms: Potassium channel subfamily T member 1 (Sequence like a calcium-activated potassium channel subunit)
Target Description: Potassium channel subfamily T member 1 or -KCNT1/Slo2.2/Slack K+ channel is encoded by the gene KCNT1. Slo2.2 is a member of the the voltage-gated ion channel (vic) superfamily, and the KCNT protein family, which is made of KCNT1 and KCNT2. Slo2.2 functions as an outwardly rectifying potassium channel subunit to contribute to ion conductance and signaling pathways. Slo2.2 can be activated by high intracellular sodium or chloride levels. Slo2.2 is expressed at the membrane in many areas of the brain, brainstem, spinal cord, spleen and liver. Mutations in this gene cause the early-onset epileptic disorders
Gene Name Alternatives: Kcnt1 Slack
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Poids moléculaire
- 140 kDa
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NCBI Accession
- NP_068625
Antigène
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