CD38 anticorps

N° du produit ABIN135205

Cet anticorps Rat Monoclonal détecte spécifiquement CD38 dans FACS, IP, ELISA, IHC (fro), Act, St, BR, DD, AD, Sep et CoSt. Il présente une réactivité avec des échantillons de Souris.

Aperçu rapide pour CD38 anticorps (ABIN135205)

Antigène: CD38

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp CD38 est non-conjugé

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Activation (Act), Stimulation (St), Blocking Reagent (BR), Drug Delivery (DD), Apoptosis Detection (AD), Separation (Sep), Co-Stimulation (CoSt)

Clone: NIMR-5

Détail du produit anti-CD38 anticorps

Fonction: Rat Anti-Mouse CD38-LE/AF

Specificité: Mouse CD38, Mr 42 kDa

Attributs du produit: Low Endotoxin/Azide Free Anti-Mouse CD38 antibody for use in flow cytometry, immunohistochemistry, immunoprecipitation, ELISA, separation, activation, costimulation, stimulation, apoptosis, drug delivery, and blocking assays.

niveau d'endotoxine: Low Endotoxin

Immunogène: BCL1 plasma membrane glycoproteins

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Phosphate buffered saline, pH 7.4

Agent conservateur: Azide free

Conseil sur la manipulation: Each reagent is stable for the period shown on the bottle label if stored as directed.

Stock: 4 °C

Stockage commentaire: 2-8°C

Détails sur CD38

Antigène: CD38

Sujet: Murine CD38, a type II transmembrane glycoprotein, is a bifunctional ectoenzyme capable of catabolizing nicotinamide adenine dinucleotide (NAD+) to cyclic ADP-ribose (cADPR), and then hydrolyzing cADPR to adenosine diphosphoribose (ADPR). It is expressed at high levels on the surface of peripheral B-lineage cells, and at low density on germinal center B cells from unimmunized mice. It has also been reported to be expressed at moderate levels on NK cells, a proportion of peripheral T cells, and a subpopulation of thymocytes which are mostly TCR+, CD4-, CD8-. Murine CD38 is also expressed by all Mac-1+ macrophages in the peritoneal cavities of unimmunized mice, but not by unstimulated bone-marrow-derived macrophages. Monoclonal antibodies to CD38 have been shown to induce B- and T-cell proliferation, protect B cells from apoptosis, and inhibit B lymphopoiesis.

ID gène: 12494

UniProt: P56528